on-invasive markers for colorectal cancer screening.
- Conditions
- colorectal cancer, colorectal neoplasia, colorectal neoplasms, high risk population, family history
- Registration Number
- NL-OMON23263
- Lead Sponsor
- Maastricht University Medical Center
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 410
Inclusion Criteria
This population will include patients with hereditary forms of CRC (Lynch syndrome or FAP) as well as patients fulfilling the criteria for familial CRC syndrome:
i) ³ 1 first degree relative (FDR) with CRC diagnosed < 50 year or
Exclusion Criteria
Individuals will be excluded if:
1.Younger than 18 years of age
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Diagnostic accuracy of molecular and protein markers in screening for colorectal neoplasia in subjects at high-risk for CRC and CRC patients, in comparison with average-risk subjects.<br><br>
- Secondary Outcome Measures
Name Time Method The role of non-invasive markers in risk stratification of patients at high-risk for CRC.