Effect of vitamin D3 supplementation on polycystic ovarian syndrome
- Conditions
- Polycystic ovarian syndrome.Polycystic ovarian syndrome
- Registration Number
- IRCT138904113140N2
- Lead Sponsor
- Research Vice-chancellor of Tabriz University of Medical Sciences and Nutrition Research Center of T
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 50
diagnosis of PCOS based on Rotterdam criteria (presence of two of the three following characteristics: 1. oligomemorreha /amenorrhea, 2. chemical or clinical finding of hyperandrogenism and 3. polycystic appearance of ovary), voluntary consent for participation in the study, age of 16-40 years, gender: female. Exclusion criteria: Other common causes of hyperandrogenemia and/or anovulation; hyperprolactinoma, congenital adrenal hyperplasia, Cushing syndrome, and virilizing ovarian or adrenal tumors, diabetes mellitus and heart, kidney and liver dysfunction, using vitamin D or Calcium supplement, metformin or insulin sensitizing drugs, corticosteroids, anticonvulsants during last 2 month or during the study, Smoking, alcohol abuse, breast feeding and pregnancy.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of gelycemic parameters. Timepoint: 60 days. Method of measurement: serum level of blood suger and fasting Insulin.;Lipid profile and hs-CRP. Timepoint: 60 days. Method of measurement: Serum level of HDL, LDL, Total Cholesterol, TG, ApoA1, hs-CRP.;Serum level of alkaline phosphatase, calcium and phosphorus. Timepoint: 60 days. Method of measurement: serum level.
- Secondary Outcome Measures
Name Time Method Antropometric indicators (BMI). Timepoint: 60 days. Method of measurement: Body weight without shoes with calibrated scale, Standing height without shoes are measuredl. BMI was calculated with this equation: W(kg) /H(m)2.;Dietary regime. Timepoint: 60 days. Method of measurement: 3 days 24h dietaty racall.