Association Between Emergency Room Evaluation and Recommendations Tool (ER2) Frailty Levels and Incident Adverse Health Events in Older Community Dwellers: Results of the NuAge Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Frailty
- Sponsor
- Jewish General Hospital
- Enrollment
- 1741
- Primary Endpoint
- Physical functional decline
- Last Updated
- 5 years ago
Overview
Brief Summary
Older adults' health and functional status are heterogeneous because of the various cumulative effects of chronic diseases and physiologic decline, contributing to a vicious cycle of increased frailty 1-4. Thanks to advances in medicine and hygiene, a growing number of older adults spend more years with a greater range of chronic diseases causing disability but not mortality 5. Health systems need to face this new challenge 4,5. Quantification of frailty and its association with the occurrence of incident adverse health events (i.e., functional decline, unplanned hospitalizations) is crucial to understand how health systems may efficiently respond to this situation 6. This study aims to examine the association of the ER2 tool score and its stratification in three levels for incident adverse health events in older community dwellers and to compare this association with three validity frailty indexes which are the Cardiovascular Health Study (CHS) frailty index, Study of Osteoporotic Fracture (SOF) index and Rockwood frailty index.
Investigators
Cyrille Launay
Principal Investigator
Jewish General Hospital
Eligibility Criteria
Inclusion Criteria
- •All enrolled participants of NuAge Study who agreed to be part of the NuAge Database and Biobank for future research purposes
Exclusion Criteria
- •Missing data
- •Participants' refusal to use their data for a purpose not identified during their recruitment.
Outcomes
Primary Outcomes
Physical functional decline
Time Frame: 4 years
annual variation of physical functional score available in the Nuage database
Hospitalizations
Time Frame: 4 years
presence or absence of hospitalizations, information available in the Nuage database
ER2
Time Frame: 4 years
6-item questionnaire determining a stratification of frailty risk in three levels (Low, moderate, high)
SOF index
Time Frame: 4 years
index with 3 items determining a level of frailty from 0 (patient is vigorous) to 1 (patient is pre-frail)
CHS index
Time Frame: 4 years
index with 5 items determining a level of frailty from 0 component positive (patient is vigorous), 1 or 2 positive components (patient is in an intermediate stage) to 3 or more positive components (patients is frail)
Rockwood index
Time Frame: 4 years
index determining a level of frailty from 0 to 17 (less than 5: patient is vigorous, between 6 and 11 patient is apparently vulnerable and above 12 patient is in severe frailty)
Mortality
Time Frame: 4 years
death of the participant, information available in the Nuage database
Falls
Time Frame: 4 years
presence or absence of falls, information available in the Nuage database