Association Between Emergency Room Evaluation and Recommendations Tool (ER2) Frailty Levels and Incident Adverse Health Events in Older Community Dwellers: Results of the NuAge Study
试验速览
- 阶段
- 不适用
- 入组人数
- 1,741
- 主要终点
- Physical functional decline
研究概览
简要总结
Older adults' health and functional status are heterogeneous because of the various cumulative effects of chronic diseases and physiologic decline, contributing to a vicious cycle of increased frailty 1-4. Thanks to advances in medicine and hygiene, a growing number of older adults spend more years with a greater range of chronic diseases causing disability but not mortality 5. Health systems need to face this new challenge 4,5. Quantification of frailty and its association with the occurrence of incident adverse health events (i.e., functional decline, unplanned hospitalizations) is crucial to understand how health systems may efficiently respond to this situation 6. This study aims to examine the association of the ER2 tool score and its stratification in three levels for incident adverse health events in older community dwellers and to compare this association with three validity frailty indexes which are the Cardiovascular Health Study (CHS) frailty index, Study of Osteoporotic Fracture (SOF) index and Rockwood frailty index.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All enrolled participants of NuAge Study who agreed to be part of the NuAge Database and Biobank for future research purposes
排除标准
- •Missing data
- •Participants' refusal to use their data for a purpose not identified during their recruitment.
结局指标
主要结局
Physical functional decline
时间窗: 4 years
annual variation of physical functional score available in the Nuage database
Hospitalizations
时间窗: 4 years
presence or absence of hospitalizations, information available in the Nuage database
ER2
时间窗: 4 years
6-item questionnaire determining a stratification of frailty risk in three levels (Low, moderate, high)
SOF index
时间窗: 4 years
index with 3 items determining a level of frailty from 0 (patient is vigorous) to 1 (patient is pre-frail)
CHS index
时间窗: 4 years
index with 5 items determining a level of frailty from 0 component positive (patient is vigorous), 1 or 2 positive components (patient is in an intermediate stage) to 3 or more positive components (patients is frail)
Rockwood index
时间窗: 4 years
index determining a level of frailty from 0 to 17 (less than 5: patient is vigorous, between 6 and 11 patient is apparently vulnerable and above 12 patient is in severe frailty)
Mortality
时间窗: 4 years
death of the participant, information available in the Nuage database
Falls
时间窗: 4 years
presence or absence of falls, information available in the Nuage database
次要结局
未报告次要终点
研究者
Cyrille Launay
Principal Investigator
Jewish General Hospital