Screening for Early Cervical Cancer Detection

Active, not recruiting

• Conditions: Cervical Cancer; Cervix Neoplasm

• Registration Number: NCT06550583
• Lead Sponsor: Assiut University

Brief Summary

This study is to audit results and adherence to Cervical Screening program before and after the implementing awareness of the WHO guidelines of screening among the multidisciplinary healthcare workers and patients.

Detailed Description

Cervical cancer screening is the asymptomatic detection of pre-cancer and cancer in women at risk, with at least one screening suggested for women aged 30-49 years. According to the World Health Survey (2015), 19% of eligible women in developing countries and 63% of those in developed nations had their cervical cancer screening done using a Pap smear or visual inspection with acetic acid (VIA).

According to latest estimates by World Health Organization (WHO), in Egypt, 866 women are diagnosed with cervical cancer every year and 373 die from the disease. Cervical cancer is the 13th most common cancer in women in Egypt and the 10th most common cancer in women aged between 15 to 44 years . Statistics from Egyptian studies provide pre invasive cervical lesion incidence levels of 0.3 % to 0.5 % .

The human papillomavirus (HPV) is one of the most significant risk factors for cervical cancer. HPV can be transmitted through sexual contact, including vaginal or oral sex with an infected person. HPV has more than 100 strains, of which HPV16 and HPV18 account for about 70% of invasive cervical cancers

Study Timeline

• Study Start: 2023-06-01
• Status Verified: 2024-08
• Study First Submitted: 2024-08-05
• Study First Submitted QC: 2024-08-08
• Last Update Submitted: 2024-08-08
• Study First Posted: 2024-08-13
• Last Update Posted: 2024-08-13
• Primary Completion: 2024-08-30
• Study Completion: 2024-09-30

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

• Women 20-60 years.

  • Sexually active.
  • Fulfilling Cervical Check's eligibility criteria for screening at the time of the audit https://www.cervicalcheck.ie/_fileupload/File/Eligibility%20Framework.pdf

Exclusion Criteria

Patient who had underwent to total hysterectomy.

• Pregnant or postpartum or post abortive patients
• Patient having any history of treatment for cervical dysplasia.
• Immunocompromised patients.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Screening clinic in Women & Children Hospital	Baseline	All women undergo Pap smear test according to inclusion criteria and will be adherence to screening program protocol

Secondary Outcome Measures

Name	Time	Method
Via test	baseline	Via test will be done to all patients come to screening clinic and Adherence to screening program protocol

Trial Locations

Locations (1)

Assiut University; 🇪🇬 Assiut, Egypt