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Understanding Recovery: Two Types of Anaesthesia Used in Breast Lump Removal

Phase 2
Not yet recruiting
Conditions
Medical and Surgical,
Registration Number
CTRI/2025/05/086086
Lead Sponsor
Government Rajaji Hospital Madurai Medical College
Brief Summary

A surgical procedure performed on a patient admitted and discharged on the same day of surgery is an accepted practice to make hospital resources available for a greater number of patients as each patient gets discharged earlier from the hospital Rapid induction and recovery may lead to faster operating room turnover shorter recovery room stay and earlier discharge to home



Propofol has low lipid solubility and it gets eliminated rapidly from circulation Propofol is proven intravenous anaesthetic agent for day care procedures due to rapid onset of action with early recovery less incidence of post operative nausea and vomiting

Sevoflurane is non inflammable highly fluorinated anaesthetic agent with pleasant smell  It is potent hypnotic and fairly non irritant to the upper airway Sevoflurane has low blood gas co- efficient and produces characteristics of fast induction and rapid emergence from anaesthesia Inhalational induction using sevoflurane is rapid smooth and well tolerated in both children and adults



Propofol based anaesthesia is associated with hypotension, bradycardia pain on injection and may have allergic reaction Sevoflurane based anaesthesia provides relatively stable hemodynamics  Many studies have been done for phase I recovery but not much work done on phase II recovery with respect to ready for discharge home criteria So we conducted this study to compare recovery profile in both groups Our primary goal was to assess and compare phase I - early recovery time to achieve Aldrete score more than 9 in recovery room as well as phase 2  discharge to home recovery time to achieve PADSS score more than 9 in both the groups

Our secondary goal was to assess and compare induction quality in terms of LMA insertion conditions in both the groups

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
Female
Target Recruitment
60
Inclusion Criteria

ASA 1 and ASA 2 Patient , those who are willing to give informed written consent.

Exclusion Criteria

1.Patient on sedative or opioid medications 2.Psychiatric or neurological disease 3.Susceptible to malignant Hyperthermia 4.Patient with significant cognitive impairment 5.Airway MPG 3 and 4 6.Lack of consent.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Time from end of procedure to 1.first spontaneous movement, 2.spontaneous eyeOutcome assessments will be conducted at baseline pre-anaesthesia, intraoperative period, immediate postoperative period 30 min, 1 hr, 2 hrs, short-term recovery 4 hrs, 8 hrs, and on postoperative day 1 24 hrs after surgery.
openingOutcome assessments will be conducted at baseline pre-anaesthesia, intraoperative period, immediate postoperative period 30 min, 1 hr, 2 hrs, short-term recovery 4 hrs, 8 hrs, and on postoperative day 1 24 hrs after surgery.
3.removal of LMAOutcome assessments will be conducted at baseline pre-anaesthesia, intraoperative period, immediate postoperative period 30 min, 1 hr, 2 hrs, short-term recovery 4 hrs, 8 hrs, and on postoperative day 1 24 hrs after surgery.
4.Followed verbal commands 5.Became fully oriented toOutcome assessments will be conducted at baseline pre-anaesthesia, intraoperative period, immediate postoperative period 30 min, 1 hr, 2 hrs, short-term recovery 4 hrs, 8 hrs, and on postoperative day 1 24 hrs after surgery.
time and placeOutcome assessments will be conducted at baseline pre-anaesthesia, intraoperative period, immediate postoperative period 30 min, 1 hr, 2 hrs, short-term recovery 4 hrs, 8 hrs, and on postoperative day 1 24 hrs after surgery.
Secondary Outcome Measures
NameTimeMethod
1.Time to achieve Aldrete score more than 9 phase 1 recovery2.Time to achieve PADSS score more than 9 Phase 2 recovery

Trial Locations

Locations (1)

Government Rajaji Hospital

🇮🇳

Madurai, TAMIL NADU, India

Government Rajaji Hospital
🇮🇳Madurai, TAMIL NADU, India
DRVIGNESHMJ
Principal investigator
9489029414
vignesh.jayaprakash94@gmail.com

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