Acupuncture and/or Diclectin Treatment for Nausea and Vomiting of Pregnancy : A Two by Two factorial Trial (NVPAct)

First Affiliated Hospital of Heilongjiang University of Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

试验速览

暂无简介。

•1. Subjects aged 20 to 45 years;
•2. Subjects who were pregnant for 7-14 weeks (49-98 days, calculated according to the last menstruation);
•3. Subjects whose score of pregnancy nausea and vomiting scale >=6;
•4. Subjects whose body weight is less than 20% of normal body weight at the early stage of pregnancy;
•5. Subjects with pregnancy (singleton / multifetal) proved by ultrasound;
•6. Subjects willing to sign informed consent.

•1. Patients with major diseases, such as malignant tumor, acute or subacute hepatitis, severe aplastic anemia, idiopathic thrombocytopenic purpura, acute appendicitis, acute pancreatitis, torch syndrome;
•2. Patients with chronic diseases, such as diabetes, coronary heart disease, and chronic hypertension;
•3. Patients with other vomiting diseases, such as thyroid disease, gastroenteritis history, gastrointestinal disease, infectious disease, trophoblastic disease, psychological disorders, etc;
•4. Patients with asthma, high intraocular pressure, narrow angle glaucoma, peptic ulcer, pyloric obstruction, bladder neck obstruction and other diseases;
•5. Patients who use other antiemetics, such as vitamin B6, ondansetron, metoclopramide, prednisone, etc
•6. Patients who are effective in conservative treatment (adjustment of diet and life style);
•7. Patients with abnormal physical examination or laboratory examination;
•8. Patients with mental disorders;
•9. Patients who are allergic to doxyramine, other antihistamines, pyridoxine hydrochloride and any non active ingredients in diclicin;
•10. Patients with monoamine oxidase (MAO) inhibitors;
•11. The object of driving or operating heavy machinery;
•12. Subjects who use alcohol or other central nervous system inhibitors such as diazepam, phenobarbital, etc.

发起方

First Affiliated Hospital of Heilongjiang University of Chinese Medicine