NCT06393257
Recruiting
Not Applicable
Efficacy and Safety of Airway Clearance Technique by Oscillation and Lung Expansion in Patients With Bronchiectasis
Shanghai Pulmonary Hospital, Shanghai, China3 sites in 1 country96 target enrollmentSeptember 1, 2023
ConditionsBronchiectasis Adult
Overview
- Phase
- Not Applicable
- Intervention
- Oscillation and Lung Expansion
- Conditions
- Bronchiectasis Adult
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
- Enrollment
- 96
- Locations
- 3
- Primary Endpoint
- sputum volume in 24h
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this prospective randomized controlled trial is to explore the efficacy and safety of Oscillation and Lung Expansion-a airway clearance technology-in bronchiectasis. Participants will receive Oscillation and Lung Expansion or postural drainage randomly in this study. and the symptom, quality of life scores and amount of expectoration will be compared between the two groups.
Investigators
Jin-Fu Xu
Professor
Shanghai Pulmonary Hospital, Shanghai, China
Eligibility Criteria
Inclusion Criteria
- •patients with acute exacerbation of bronchiectasis
Exclusion Criteria
- •Haemoptysis greater than 50ml
- •state of endangerment
- •pneumothorax
- •Lung surgery history within 6 months
- •Severe heart, brain and nervous system diseases
Arms & Interventions
Oscillation and Lung Expansion
Intervention: Oscillation and Lung Expansion
Oscillation and Lung Expansion
Intervention: Anti-infective therapy
Oscillation and Lung Expansion
Intervention: Mucolytic
postural drainage
Intervention: Postural drainage
postural drainage
Intervention: Anti-infective therapy
postural drainage
Intervention: Mucolytic
Outcomes
Primary Outcomes
sputum volume in 24h
Time Frame: 2 weeks
Secondary Outcomes
- Bronchiectasis exacerbation and symptom tool(Assessed at baseline, 2 weeks, 4 weeks, 8 weeks and 12 weeks post-discharge)
- Quality of life questionnaire-bronchiectasis(Assessed at baseline, 2 weeks, 4 weeks, 8 weeks and 12 weeks post-discharge)
- Leicester Cough Questionnaire(Assessed at baseline, 2 weeks, 4 weeks, 8 weeks and 12 weeks post-discharge)
- Bronchiectasis Health Questionnaire(Assessed at baseline, 2 weeks, 4 weeks, 8 weeks and 12 weeks post-discharge)
- Time to the first bronchiectasis exacerbation since randomization(Assessed at 4 weeks, 8 weeks and 12 weeks post-discharge)
Study Sites (3)
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