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Clinical Trials/NCT06346080
NCT06346080
Recruiting
Not Applicable

Molecular Analysis for Gastro-Esophageal Cancer: Multicenter Discrete Choice Experiment

KU Leuven1 site in 1 country2,200 target enrollmentAugust 1, 2024

Overview

Phase
Not Applicable
Intervention
Survey
Conditions
Esophageal Cancer
Sponsor
KU Leuven
Enrollment
2200
Locations
1
Primary Endpoint
The percentage differences in preference of participants between geographical regions
Status
Recruiting
Last Updated
2 months ago

Overview

Brief Summary

The goal of this survey is to investigate the participants' preference for a specific screening/diagnostic tool to detect and assess gastro-esophageal cancer.

The main question it aims to answer are:

  • Which diagnostic modality is preferred by patients and the general population?
  • Which features of the diagnostic test are most detrimental in the decision-making for one or the other modality?
  • Are geographical differences present in regard to the preference for a diagnostic modality?

Participants will be asked to complete a survey of 20-25min, including a brief intake regarding their socio-economic status. This approach will allow us to correct for confounding factors.

Registry
clinicaltrials.gov
Start Date
August 1, 2024
End Date
August 1, 2026
Last Updated
2 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
KU Leuven
Responsible Party
Principal Investigator
Principal Investigator

Stijn Vanstraelen

Principal investigator

KU Leuven

Eligibility Criteria

Inclusion Criteria

  • Individuals \>18yo to 75yo (upper age limit of Barrett's surveillance)
  • Access to computer or smartphone
  • Clear understanding of available languages of the experiment (English, French, Dutch, Spanish, German, Chinese, Japanese)

Exclusion Criteria

  • Individuals less than 18yo and more than 75yo
  • Incarcerated individuals

Arms & Interventions

Survey participants

Participants who will complete a survey investigating their preference for diagnosis and assessment of gastro-esophageal cancer

Intervention: Survey

Outcomes

Primary Outcomes

The percentage differences in preference of participants between geographical regions

Time Frame: 2 years

Differences in preferences will be compared between different geographical regions using chi-squared or McNemar's test

The rate of contribution of diagnostic features to the preference of participants

Time Frame: 2 years

A part-worth analysis, expressed as percentage, from a discrete choice experiment (questionnaire) will assess the features that are most important to the participants

Secondary Outcomes

  • Assess the rate of trade-off demonstrated as odds ratio between cancer-related mortality reduction and costs(2 years)
  • Assess the rate patient-level demographics influence the importance of a test feature, expressed as an odds ratio(2 years)

Study Sites (1)

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