Identifying Optimal Smoking Cessation Intervention Components (Cessation)

Phase 4

Completed

Conditions: Smoking
Nicotine Dependence
Smoking Cessation

Interventions: Behavioral: Counseling before quit attempt
Behavioral: Minimal In-person counseling during quit attempt
Behavioral: Intensive in-person counseling during the quit attempt
Behavioral: Minimal phone counseling during the quit attempt
Behavioral: Intensive phone counseling during the quit attempt
Drug: Short Term Nicotine Patch + Nicotine Gum during the quit attempt
Drug: Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt
Drug: Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum
Drug: Pre-Quit Nicotine Patch
Drug: Pre-Quit Nicotine Gum

Registration Number: NCT01116986

Lead Sponsor: University of Wisconsin, Madison

Brief Summary: The goal of this research is to identify the best smoking cessation intervention components to be combined into a state-on-the-art, comprehensive smoking cessation intervention. This research examines the ability of different interventions, provided both prior to and after the quit attempt, to maximize the ability to initially quit and then stay quit. The investigators will be examining six different treatment interventions: pre-quit nicotine patch, pre-quit nicotine gum, pre-quit counseling, post-quit in-person counseling, post-quit phone counseling and duration of post-quit nicotine replacement therapy.

Detailed Description: Not available

Recruitment & Eligibility

Status: COMPLETED

Sex: All

Target Recruitment: 637

Inclusion Criteria

18 years of age or older;
Report smoking at least 5 cigarettes per day for the previous 6 months;
Able to read and write English;
Agree to attend visits, to respond to coaching calls, and to respond to Interactive Voice Response (IVR) phone prompts;
Plans to remain in the intervention catchment area for at least 12 months;
Currently interested in quitting smoking (defined as would like to try to quit in the next 30 days).
All women of childbearing potential will be required to agree to use an acceptable method of birth control to prevent pregnancy during the study.

Exclusion Criteria

Currently taking bupropion, Wellbutrin, chantix or varenicline (current use of NRT is not exclusionary if the participant agrees to use only study medication for the duration of the study);
Study candidate is pregnant, trying to get pregnant, or nursing.
A history of psychosis or bipolar disorder
A history of skin or allergic reactions while using a nicotine patch.
Had a heart attack, stroke, or abnormal electrocardiogram within the past 4 weeks.

Study & Design

Study Type: INTERVENTIONAL

Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
1, Patch, Gum, Prequit, Min In-Person, Min Phone, 8Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
1, Patch, Gum, Prequit, Min In-Person, Min Phone, 8Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
1, Patch, Gum, Prequit, Min In-Person, Min Phone, 8Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
1, Patch, Gum, Prequit, Min In-Person, Min Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
1, Patch, Gum, Prequit, Min In-Person, Min Phone, 8Wk	Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
2, Patch, Gum, Prequit, Min In-Person, Int Phone, 16Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
2, Patch, Gum, Prequit, Min In-Person, Int Phone, 16Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
2, Patch, Gum, Prequit, Min In-Person, Int Phone, 16Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
2, Patch, Gum, Prequit, Min In-Person, Int Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
2, Patch, Gum, Prequit, Min In-Person, Int Phone, 16Wk	Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
3, Patch, Gum, Prequit, Int In-Person, Min Phone, 16Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
3, Patch, Gum, Prequit, Int In-Person, Min Phone, 16Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
3, Patch, Gum, Prequit, Int In-Person, Min Phone, 16Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
4, Patch, Gum, Prequit, Int In-Person, Int Phone, 8Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
4, Patch, Gum, Prequit, Int In-Person, Int Phone, 8Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
3, Patch, Gum, Prequit, Int In-Person, Min Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
3, Patch, Gum, Prequit, Int In-Person, Min Phone, 16Wk	Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
4, Patch, Gum, Prequit, Int In-Person, Int Phone, 8Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
4, Patch, Gum, Prequit, Int In-Person, Int Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
4, Patch, Gum, Prequit, Int In-Person, Int Phone, 8Wk	Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
5, Patch, Gum, No Prequit, Min In-Person, Min Phone, 16Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
5, Patch, Gum, No Prequit, Min In-Person, Min Phone, 16Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
5, Patch, Gum, No Prequit, Min In-Person, Min Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
5, Patch, Gum, No Prequit, Min In-Person, Min Phone, 16Wk	Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
6, Patch, Gum, No Prequit, Min In-Person, Int Phone, 8Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
6, Patch, Gum, No Prequit, Min In-Person, Int Phone, 8Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
6, Patch, Gum, No Prequit, Min In-Person, Int Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
6, Patch, Gum, No Prequit, Min In-Person, Int Phone, 8Wk	Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
7, Patch, Gum, No Prequit, Int In-Person, Min Phone, 8Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
7, Patch, Gum, No Prequit, Int In-Person, Min Phone, 8Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
7, Patch, Gum, No Prequit, Int In-Person, Min Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
7, Patch, Gum, No Prequit, Int In-Person, Min Phone, 8Wk	Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
8, Patch, Gum, No Prequit, Int In-Person, Int Phone, 16Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
8, Patch, Gum, No Prequit, Int In-Person, Int Phone, 16Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
8, Patch, Gum, No Prequit, Int In-Person, Int Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
8, Patch, Gum, No Prequit, Int In-Person, Int Phone, 16Wk	Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
9, Patch, No Gum, Prequit, Min In-Person, Min Phone, 16Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
9, Patch, No Gum, Prequit, Min In-Person, Min Phone, 16Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
9, Patch, No Gum, Prequit, Min In-Person, Min Phone, 16Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
9, Patch, No Gum, Prequit, Min In-Person, Min Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
9, Patch, No Gum, Prequit, Min In-Person, Min Phone, 16Wk	Pre-Quit Nicotine Patch	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
10, Patch, No Gum, Prequit, Min In-Person, Int Phone, 8Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
10, Patch, No Gum, Prequit, Min In-Person, Int Phone, 8Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
10, Patch, No Gum, Prequit, Min In-Person, Int Phone, 8Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
10, Patch, No Gum, Prequit, Min In-Person, Int Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
10, Patch, No Gum, Prequit, Min In-Person, Int Phone, 8Wk	Pre-Quit Nicotine Patch	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
11, Patch, No Gum, Prequit, Int In-Person, Min Phone, 8Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
11, Patch, No Gum, Prequit, Int In-Person, Min Phone, 8Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
11, Patch, No Gum, Prequit, Int In-Person, Min Phone, 8Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
11, Patch, No Gum, Prequit, Int In-Person, Min Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
11, Patch, No Gum, Prequit, Int In-Person, Min Phone, 8Wk	Pre-Quit Nicotine Patch	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
12, Patch, No Gum, Prequit, Int In-Person, Int Phone, 16Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
12, Patch, No Gum, Prequit, Int In-Person, Int Phone, 16Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
12, Patch, No Gum, Prequit, Int In-Person, Int Phone, 16Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
12, Patch, No Gum, Prequit, Int In-Person, Int Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
12, Patch, No Gum, Prequit, Int In-Person, Int Phone, 16Wk	Pre-Quit Nicotine Patch	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
13, Patch, No Gum, No Prequit, Min In-Person, Min Phone, 8Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
13, Patch, No Gum, No Prequit, Min In-Person, Min Phone, 8Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
13, Patch, No Gum, No Prequit, Min In-Person, Min Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
13, Patch, No Gum, No Prequit, Min In-Person, Min Phone, 8Wk	Pre-Quit Nicotine Patch	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
14, Patch, No Gum, No Prequit, Min In-Person, Int Phone, 16Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
14, Patch, No Gum, No Prequit, Min In-Person, Int Phone, 16Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
14, Patch, No Gum, No Prequit, Min In-Person, Int Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
14, Patch, No Gum, No Prequit, Min In-Person, Int Phone, 16Wk	Pre-Quit Nicotine Patch	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
15, Patch, No Gum, No Prequit, Int In-Person, Min Phone, 16Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
15, Patch, No Gum, No Prequit, Int In-Person, Min Phone, 16Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
15, Patch, No Gum, No Prequit, Int In-Person, Min Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
15, Patch, No Gum, No Prequit, Int In-Person, Min Phone, 16Wk	Pre-Quit Nicotine Patch	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
16, Patch, No Gum, No Prequit, Int In-Person, Int Phone, 8Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
16, Patch, No Gum, No Prequit, Int In-Person, Int Phone, 8Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
16, Patch, No Gum, No Prequit, Int In-Person, Int Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
16, Patch, No Gum, No Prequit, Int In-Person, Int Phone, 8Wk	Pre-Quit Nicotine Patch	This arm of the project will address the following question: How effective is the following Intervention? Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
17, No Patch, Gum, Prequit, Min In-Person, Min Phone, 16Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
17, No Patch, Gum, Prequit, Min In-Person, Min Phone, 16Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
17, No Patch, Gum, Prequit, Min In-Person, Min Phone, 16Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
17, No Patch, Gum, Prequit, Min In-Person, Min Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
17, No Patch, Gum, Prequit, Min In-Person, Min Phone, 16Wk	Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
18, No Patch, Gum, Prequit, Min In-Person, Int Phone, 8Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
18, No Patch, Gum, Prequit, Min In-Person, Int Phone, 8Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
18, No Patch, Gum, Prequit, Min In-Person, Int Phone, 8Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
18, No Patch, Gum, Prequit, Min In-Person, Int Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
18, No Patch, Gum, Prequit, Min In-Person, Int Phone, 8Wk	Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
19, No Patch, Gum, Prequit, Int In-Person, Min Phone, 8Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
19, No Patch, Gum, Prequit, Int In-Person, Min Phone, 8Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
19, No Patch, Gum, Prequit, Int In-Person, Min Phone, 8Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
19, No Patch, Gum, Prequit, Int In-Person, Min Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
19, No Patch, Gum, Prequit, Int In-Person, Min Phone, 8Wk	Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
20, No Patch, Gum, Prequit, Int In-Person, Int Phone, 16Wk	Counseling before quit attempt	How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
20, No Patch, Gum, Prequit, Int In-Person, Int Phone, 16Wk	Intensive in-person counseling during the quit attempt	How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
20, No Patch, Gum, Prequit, Int In-Person, Int Phone, 16Wk	Intensive phone counseling during the quit attempt	How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
20, No Patch, Gum, Prequit, Int In-Person, Int Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
20, No Patch, Gum, Prequit, Int In-Person, Int Phone, 16Wk	Pre-Quit Nicotine Gum	How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
21, No Patch, Gum, No Prequit, Min In-Person, Min Phone, 8Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
21, No Patch, Gum, No Prequit, Min In-Person, Min Phone, 8Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
21, No Patch, Gum, No Prequit, Min In-Person, Min Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
21, No Patch, Gum, No Prequit, Min In-Person, Min Phone, 8Wk	Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
22, No Patch, Gum, No Prequit, Min In-Person, Int Phone, 16Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
22, No Patch, Gum, No Prequit, Min In-Person, Int Phone, 16Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
22, No Patch, Gum, No Prequit, Min In-Person, Int Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
22, No Patch, Gum, No Prequit, Min In-Person, Int Phone, 16Wk	Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
23, No Patch, Gum, No Prequit, Int In-Person, Min Phone, 16Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
23, No Patch, Gum, No Prequit, Int In-Person, Min Phone, 16Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
23, No Patch, Gum, No Prequit, Int In-Person, Min Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
23, No Patch, Gum, No Prequit, Int In-Person, Min Phone, 16Wk	Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
24, No Patch, Gum, No Prequit, Int In-Person, Int Phone, 8Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
24, No Patch, Gum, No Prequit, Int In-Person, Int Phone, 8Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
24, No Patch, Gum, No Prequit, Int In-Person, Int Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
24, No Patch, Gum, No Prequit, Int In-Person, Int Phone, 8Wk	Pre-Quit Nicotine Gum	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
25, No Patch, No Gum, Prequit, Min In-Person, Min Phone, 8Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
25, No Patch, No Gum, Prequit, Min In-Person, Min Phone, 8Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
25, No Patch, No Gum, Prequit, Min In-Person, Min Phone, 8Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
25, No Patch, No Gum, Prequit, Min In-Person, Min Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
26, No Patch, No Gum, Prequit, Min In-Person, Int Phone, 16Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
26, No Patch, No Gum, Prequit, Min In-Person, Int Phone, 16Wk	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
26, No Patch, No Gum, Prequit, Min In-Person, Int Phone, 16Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
26, No Patch, No Gum, Prequit, Min In-Person, Int Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
27, No Patch, No Gum, Prequit, Int In-Person, Min Phone, 16Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
27, No Patch, No Gum, Prequit, Int In-Person, Min Phone, 16Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
27, No Patch, No Gum, Prequit, Int In-Person, Min Phone, 16Wk	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
27, No Patch, No Gum, Prequit, Int In-Person, Min Phone, 16Wk	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
28, No Patch, No Gum, Prequit, Int In-Person, Int Phone, 8Wk	Counseling before quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
28, No Patch, No Gum, Prequit, Int In-Person, Int Phone, 8Wk	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
28, No Patch, No Gum, Prequit, Int In-Person, Int Phone, 8Wk	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
28, No Patch, No Gum, Prequit, Int In-Person, Int Phone, 8Wk	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
29, No Patch, No Gum, No Prequit, Min In-Person, Min Phone, 16	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
29, No Patch, No Gum, No Prequit, Min In-Person, Min Phone, 16	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
29, No Patch, No Gum, No Prequit, Min In-Person, Min Phone, 16	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
30, No Patch, No Gum, No Prequit, Min In-Person, Int Phone, 8W	Minimal In-person counseling during quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
30, No Patch, No Gum, No Prequit, Min In-Person, Int Phone, 8W	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
30, No Patch, No Gum, No Prequit, Min In-Person, Int Phone, 8W	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
31, No Patch, No Gum, No Prequit, Int In-Person, Min Phone, 8W	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
31, No Patch, No Gum, No Prequit, Int In-Person, Min Phone, 8W	Minimal phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
31, No Patch, No Gum, No Prequit, Int In-Person, Min Phone, 8W	Short Term Nicotine Patch + Nicotine Gum during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Minimal Phone counseling during quit attempt, 8Wk Medication duration during quit attempt
32, No Patch, No Gum, No Prequit, Int In-Person, Int Phone, 16	Intensive in-person counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
32, No Patch, No Gum, No Prequit, Int In-Person, Int Phone, 16	Intensive phone counseling during the quit attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt
32, No Patch, No Gum, No Prequit, Int In-Person, Int Phone, 16	Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt	This arm of the project will address the following question: How effective is the following Intervention? No Prequit Nicotine Patch, No Prequit Nicotine Gum, No Counseling before quit attempt, Intensive In-person counseling during quit attempt, Intensive Phone counseling during quit attempt, 16Wk Medication duration during quit attempt

Primary Outcome Measures

Name	Time	Method
Self-Reported 7-Day Point-Prevalence Abstinence	16 weeks post-quit	Self-Reported 7-Day Point-Prevalence Abstinence is a dichotomous outcome with values of 0 and 1 where 0=smoking on one or more of the past 7 days at the assessment endpoint (16 weeks post-quit) and 1=no smoking on any of the past 7 days at the assessment endpoint (i.e., abstinent for the past 7 days); this outcome will be analyzed in a logistic regression analysis model. Note: This abstinence primary outcome replaces latency to relapse (now designated as a secondary outcome) because reviewers of the now-accepted manuscript (at the journal "Addiction") advised us to change the primary outcome to the current week 16 Self-Reported 7-Day Point-Prevalence Abstinence outcome.

Secondary Outcome Measures

Name	Time	Method
Latency to Relapse	During the first 6 months post-quit	Latency to Relapse during the first 6 months post-quit, with relapse defined as 7 consecutive days of smoking; this outcome will be analyzed in a Cox regression survival analysis model with non-relapsers coded as right-censored.

Trial Locations

Locations (1): University of Wisconsin Center for Tobacco Research and Intervention, School of Medicine and Public Health
🇺🇸
Madison, Wisconsin, United States