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Safety and usefulness of Enoxaparin versus unfractionated heparin in patients with ST elevation myocardial infarctio

Phase 3
Conditions
Ischaemic heart diseases.
Acute myocardial infarction
Registration Number
IRCT138711271695N1
Lead Sponsor
Tehran University of Medical Sciences and Health Services
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
150
Inclusion Criteria

Inclusion Criteria: Age range 18 to 75 years old, onset of symptoms of acute myocardial infarction within 12 hrs before randomization, ST-segment elevation of 0.1 mV or more in two or more limbs leads or at least 0.2 mV in two or more precordial leads.

Exclusion Criteria

Contraindications to streptokinase, cardiogenic shock, receiving glycoprotein IIb/IIIa antagonists or oral anticoagulants within the prior days or therapeutic dose of heparin or low molecular-weight heparin within the previous hours, need for anticoagulant therapy and also any other disease that resulted in increasing risk

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ST-segment resolution. Timepoint: 90 minutes after intervention. Method of measurement: ECG.;Ejection Fraction. Timepoint: during 5-10th day of admission. Method of measurement: Angiography.;Thombolysis in Myocardial Infarction (TIMI) flow grade 3 (patency). Timepoint: during 5-10th day of admission. Method of measurement: Through angiography.
Secondary Outcome Measures
NameTimeMethod
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