Gut microbiome alterations in sepsis from a tertiary care hospital. - Nil

Department of Microbiology Kasturba Medical College0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年6月24日

试验速览

暂无简介。

•Patients hospitalized in intensive care units for sepsis.
•Case definition:
•Sepsis group:
•· Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection.
•· Organ dysfunction can be identified as an acute change in total SOFA score =2 points consequent to the infection.
•· The baseline SOFA score can be assumed to be zero in patients not known to have preexisting organ dysfunction.
•Control group:
•· Age matched individuals (± 5 years) with no known co-morbidities and living in the same locality as that of the sepsis group.
•· No history of previous hospitalization in the past 6 months
•· No history of consumption of antibiotics in the past 6 months.

•Sepsis group:
•Inability to obtain consent from the patient or next of kin.
•Pregnant or breastfeeding women.
•Age of the participant is less than 18 years.
•Patients with withdraw of care decision at the time of inclusion.
•Patients with restricted liberty or under legal protection.
•Second admission to ICU or previous enrollment in a study (within same hospital admission).
•Transfer from other hospital ICUs (if stay was greater than 24 hours).
•Control group: History of hospitalisation and antibiotic consumption in the past 6 months.

发起方

Department of Microbiology Kasturba Medical College