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Hypoplastic Left Heart Syndrome: Subendocardial Viability After Norwood Palliation

Terminated
Conditions
Hypoplastic Left Heart Syndrome
Registration Number
NCT05709275
Lead Sponsor
IRCCS Policlinico S. Donato
Brief Summary

This project has several objectives ranging from clinical data analysis to computational simulations as listed below:

1. Retrospective review of all patients with HLHS treated surgically and followed medically at the IRCCS Policlinico San Donato aiming to assess the SEVR after each step of Norwood palliation to analyze its influences on:

* Mortality;

* Occurrence of adverse events;

* Outcome of the three-staged palliation;

2. Creation of a prospective registry that will enroll all patients surgically treated for HLHS at the IRCCS Policlinico San Donato.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
6
Inclusion Criteria
  • Pediatric patients (age ≤18 years) with the diagnosis of hypoplastic left heart syndrome who underwent the Norwood palliation at the IRCCS Policlinico San Donato.
Exclusion Criteria
  • Patients with any type of atrioventricular discordance.
  • Pediatric patients (age ≤18 years) with the diagnosis of hypoplastic left heart syndrome who underwent the Norwood palliation at the IRCCS Policlinico San Donato before March 2019.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Mortality during the hospital stay and after the discharge5 year

death, cardiovascular arrest

Secondary Outcome Measures
NameTimeMethod
Number of adverse events registered during the follow-up.5 year

Patients will be followed prospectively with their normal routine cardiological follow-up for 5 years

Trial Locations

Locations (1)

IRCCS Policlinico San Donato

🇮🇹

San Donato, Milano, Italy

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