Barotrauma in Adults With Critical COVID-19
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 669
- 试验地点
- 1
- 主要终点
- Barotrauma
研究概览
简要总结
During the pandemic of COVID-19, studies reporting a high incidence of barotrauma, both pneumothorax but also pneumomediastinum, in patients with critical COVID-19. If this is complications of the respiratory support used to treat patients hypoxemia or if it is a direct consequence of COVID-19 damaging the lung tissue is not known.
The aim of this study is to investigate the incidence and type barotrauma, if there is an association between barotrauma and level of respiratory support used in the intensive care unit, and if barotrauma is associated with worse outcome compared to patients without barotrauma.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Positive polymerase chain reaction for SARS-CoV-2
- •Admitted to ICU due to respiratory failure
排除标准
- •Transferred to or from an ICU in other hospital/region making data collection regarding baseline data/outcomes not possible
结局指标
主要结局
Barotrauma
时间窗: 28 days from ICU admission
Pneumothorax, pneumomediastinum, pneumatocele or subcutaneous emphysema as verified by radiology
次要结局
未报告次要终点
研究者
Sandra Jonmarker
Consultant in intensive care and anaesthesia, Ph D
Karolinska Institutet