Exploration of clinical characteristics, prognostic factors, and genetic biomarkers of inflammatory bowel disease in Korea

Asan Medical Center0 个研究点目标入组 7,500 人开始时间: 待定最近更新: 2023年1月10日

适应症

试验速览

暂无简介。

•Crohn' disease: patients who met at least 2 of the following criteria
•a) clinical history of abdominal pain, weight loss, malaise, diarrhea,
•and/or rectal bleeding; b) endoscopic findings of mucosal
•cobblestoning, linear ulceration, skip areas, or perianal disease;
•c) radiologic findings of stricture, mucosal
•cobblestoning, or ulceration; d) macroscopic appearance of
•bowel wall induration, mesenteric lymphadenopathy, and
•creeping fat” at laparotomy; and e) pathologic findings of
•transmural inflammation and/or epithelioid granulomas. Only
•patients who met these criteria for at least 2 months are
•- Ulcerative colitis: patients who met all 3 of the following criteria
•a) a typical history of diarrhea or blood and pus or both in the stool for longer than 4 weeks; b) a typical sigmoidoscopic or colonoscopic
•picture with diffusely granular, friable, or ulcerated mucosa
•without rectal sparing or skip lesions or radiological signs of
•characteristic continuous granular or ulcerated mucosa; and
•c) characteristic histopathological signs of inflammation on
•- Controls: subjects who do not have any evidence of inflammatory bowel disease and who gave an informed consent for being enrolled in this study

发起方