Study of Effect of Apamarga Ghrita in Wound Healing.

Phase 2

Recruiting

• Conditions: Unspecified injury,

• Registration Number: CTRI/2019/01/017235
• Lead Sponsor: Rajkumar Tiwari Self

Brief Summary

This is A Randomized controlled clinical study of Apamarga Ghrita on Utsadana karma in wound healing with special refrence to Collagen Synthesis.

wound healing is very complex process involving 4 phases including Haemostasis,Inflammation,Proliferation with collagen synthesis and Maturation.Acharya Sushruta described Shashti i.e. 60 Upkramas for vrana.In which Utsadana karma has its place inbetween Shodhana and Ropana.

Apamarga ghrita,described by dalhana for Utsadana karma has been used  traditionally in wound healing and in some vivo studies have showed increased number of fibrocytes, remarkable degree of neovascularization and epithelisation which is due to the increased collagen fiber and proteins.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-25
• Last Update Posted: 2019-11-20

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• 1.Patients having wound without any major illnesses.
• 3.Post operative wounds of Fistulectomy and Haemorrhoidectomy.
• 4.Traumatic wounds.
• 5.wound size of less than 49 square centimeter.
• 6.wounds without any major complications and cooperative patients will be taken for study.

Exclusion Criteria

• 1.Patient having any major illnesses.
• 2.patient having age less than 20 years and more than 60 years.
• 3.wound of more than 24 hours duration.
• 4.wound size more than 49 square centimeter.
• 5.Immunocompromised and non cooperative patients will be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessments of Utsadana karma done by Apamarga ghrita.	0 day,5th day,10th day and 15th day.(For Total of 15 day)

Secondary Outcome Measures

Name	Time	Method
Review the literature through the Ayurvedic and modern classical text with recent research articles on Utsadana karma (Collagen Synthesis).	1 month
Compare the effect of Apamarga Ghrita with Povidone iodine ointment on Utsadana karma.	15 days

Trial Locations

Locations (1)

Government Ayurved college and hospital.; 🇮🇳 Nagpur, MAHARASHTRA, India

Government Ayurved college and hospital.

🇮🇳Nagpur, MAHARASHTRA, India

Tiwari Rajkumar

Principal investigator

8369080295

drtiwariraj@gmail.com