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Clinical Trials/NCT06696313
NCT06696313
Active, not recruiting
Not Applicable

Radiographic Migration Analysis of the Insignia Hip Stem

Canadian Radiostereometric Analysis Network1 site in 1 country25 target enrollmentJanuary 15, 2025

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hip Implant
Sponsor
Canadian Radiostereometric Analysis Network
Enrollment
25
Locations
1
Primary Endpoint
Migration
Status
Active, not recruiting
Last Updated
4 months ago

Overview

Brief Summary

The purpose of this study is to assess the migration pattern of the Insignia hip stem using radiostereometric analysis (RSA for short) and computed tomography (CT). Only patients with degenerative joint disease requiring primary total hip replacement will be asked to participate. The other purpose is to assess if there are any differences between the gold-standard RSA-measured migration and CT-RSA-measured migration. The clinical outcomes will be measured using joint function and patient satisfaction questionnaires. Approximately thirty patients will be enrolled onto the study.

Detailed Description

This is a single-centre, non-randomized, non-controlled trial of patients undergoing primary total hip arthroplasty using the Insignia hip stem. Patients will undergo RSA and CT-RSA imaging and analyses to identify migration of the femoral stem with respect to the adjuvant bone during the first 2 post-operative years. The primary outcome of this study is to determine if femoral stem stability is achieved between 6-12 month and 12-24 month post-operative intervals.

Registry
clinicaltrials.gov
Start Date
January 15, 2025
End Date
December 1, 2027
Last Updated
4 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Canadian Radiostereometric Analysis Network
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Symptomatic osteoarthritis of the hip indicating primary total hip arthroplasty - Aged 21 years or older
  • Patients willing and able to comply with follow-up requirements and self-evaluations
  • Ability to give informed consent

Exclusion Criteria

  • Active or prior infection
  • Medical condition precluding major surgery
  • Medical condition with less than 2 years life expectancy
  • Overhanging pannus (direct anterior approach)
  • Prior surgery of the hip involving implantation of hardware (i.e., hemiarthroplasty, internal fixation, pelvic reconstruction near the acetabulum requiring removal)
  • Skin condition on the area of incision
  • Multi-level lumbar spine fusion
  • Ankylosing spondylolithesis
  • Shortening osteotomy through the femur

Outcomes

Primary Outcomes

Migration

Time Frame: Up to 2 years post-operative

Quantify migration of the Insignia stem using RSA and CT-RSA

Secondary Outcomes

  • Validation(Up to 2 years post-operative)
  • Early migration(Up to 2 years post-operative)
  • Changes in Oxford-12 Hip Score from baseline(pre-op) to 6-month, 1-year and 2-year(Up to 2 years post-operative)
  • Changes in EQ-5D-5L from baseline(pre-op) to 6-month, 1-year and 2-year(Up to 2 years post-operative)
  • Changes in Patient Satisfaction (VAS) from baseline(pre-op) to 6-month, 1-year and 2-year(Up to 2 years post-operative)

Study Sites (1)

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