CTRI/2019/07/020170Not yet recruitingPhase 3
EFFECT OF RESPIRATORY PHYSIOLOGICAL CHANGES ON INTRACRANIAL PHYSIOLOGY; OPTIC NERVE SHEATH DIAMETER (ONSD) AND CEREBRAL OXYGEN SATURATION (rScO2) IN ACUTE TRAUMATIC BRAIN INJURY (TBI)
ational Institute of Mental Health and Neurosciences0 sites0 target enrollmentStarted: TBDLast updated:
Trial Snapshot
- Phase
- Phase 3
- Status
- Not yet recruiting
- Sponsor
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •Age > 18 years
- •Patients admitted to ICU < 72 hrs of acute TBI
- •Patients with baseline requirements of FiO2 <= 50% and PEEP <= 5 cm H2O
- •Haemodynamic stability
- •Focal lesion in the brain
Exclusion Criteria
- •Age <= 18 years
- •Patients with supra-normal requirements of FiO2 and PEEP
- •Patients with ophthalmological conditions (glaucoma or eye trauma)
- •Conditions where rScO2 measurement using NIRS may be unreliable
- •Conditions with persistent midline shift more than pre-op status
- •Baseline ONSD > 6 mm
- •Baseline rScO2 < 50%
Investigators
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