A Randomized Open Labelled Controlled Clinical Study to Evaluate the Efficacy of Kashmaryadi Ghrita Uttarbasti and Phala Ghrita Uttarbasti in the management of Stree Vandhyatva wsr Anovulatory Factor
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Trial drugs will help in ovulation induction of patient
研究概览
简要总结
God has bestowed women with the ability to carry forward the lineage.Acharya Charaka has specified that only women holds the power to conceive.Due to this ability a women has been given a status of high respect in the society. The importance of Santan(child) has been explained in Charaka Samhita that the love,strength ,happiness,livelihood,expansion of family ,attainment of fame,prestige in world ,future ,happy life ,satisfaction are all under the influence of children.But unfortunately many couples are devoid of this beautiful experience due to infertility. Infertility is defined as a failure to conceive within one or more years of regular unprotected intercourse.It can be classified into primary and secondary .Out of many causes ,most common cause of female infertility is anovulation i.e. 30-40% of all .This can be anovulation or severe oligo ovulation .In oligo ovulation ,ovulation does occur but in irregular frequency which decreases the chances of pregnancy . In classical texts of Ayurveda foetus is termed as “Garbha†when shukra (semen ) and aartava (ovum) meet with atma inside the kukshi ,4 vital factors are essential for Garbh(attainment of foetus ) . These are Ritu(fertile period) Kshetra (female reproductive organ) Ambu (proper nutrients and fluid ) Beeja(ovum and sperm ) In female body Beeja denotes ovum .Formation of Beeja takes place in ovary . Yoni is place of Vata and Vata plays vital role in beejotsarga and folliculogenesis by karma and swabhava .Release of egg from ovary is termed as Beejotsarga .Beeja plays crucial role in female reproductive process and in absence of this Garbha cannot be formed inspite of proper Ritu ,Kshetra and Ambu . So anovulation can be correlated with Beeja Dushti and its indeed an important factor causing infertility as per Ayurveda and modern sciences.Therefore to find an effective way of treatment for this , we will be using Kashmaryadi Ghrita Uttarbasti and Phala Ghrita Uttarbasti in the management of Vandhyatva w.s.r. to Anovulatory Factor
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 21.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •Married female of age from 21 to 40 years Patient having anovulation with or without PCOD Primary and secondary both types of infertility due to ovulatory factor defect Patients who will agree for consent necessary investigation and agreed for regular follow up Patient who will fulfill diagnostic criteria Patient willing to participate in trial.
排除标准
- •Female of age group less than 21years and more than 40 years Patient with uncontrolled HTN TB DM and any other systemic diseases Patients having benign and malignant tumors of uterus and ovaries Pregnancies are excluded Patients having bleeding disorders Patients having acute and chronic pelvic inflammatory disease STD Chromosomal abnormalities Patients having congenital anomalies of genital organs Patient having adenomyosis tubercular endometritis endometriosis tubal blockage fibroid uterus Cause of infertility in patient is other than anovulatory factor.
结局指标
主要结局
Trial drugs will help in ovulation induction of patient
时间窗: Follow up for the subjective parameters will be done after every cycle on 5th day for 3 consecutive months | Follow up for objective parameters will be done after 3 months(13 weeks) by Ultrasonography
次要结局
- Trial drugs will help in curing menstrual abnormalities associated with(anovulation like irregular & scanty /excessive menstruation)
研究者
Dr ALVIN
INSTITUTE FOR AYURVED STUDIES AND RESEARCH