NCT04548401Unknown不适用
Effect of Antiplatelet Therapy on Cognition After Aneurysmal Subarachnoid Hemorrhage
Nanjing Medical University1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2019年11月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Montreal Cognitive Assessment (MoCA) Test
研究概览
简要总结
Deficits in memory, executive function, and language are common cognitive sequelae of aneurysmal subarachnoid hemorrhage (aSAH). Previous study demonstrated that post-treatment antiplatelet therapy reduced risk for delayed cerebral ischemia caused by aSAH. However, the effect of antiplatelet therapy on cognition after aSAH is unclear. The aim of this study was to assess the effect of antiplatelet therapy on cognition after aSAH.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with SAH in whom the aneurysm was proven by conventional angiography;
- •Baseline Hunt-Hess grade I-III;
- •patients received endovascular treatment
排除标准
- •Hunt-Hess grade IV-V;
- •Non-aneurysmal SAH;
- •Dementia in other diseases;
- •Lacking of 6-8 month MoCA evaluation.
研究组 & 干预措施
Antiplatelet-Y group
Patients with ruptured aneurysm underwent stent assisted coiling, with post-treatment antiplatelet therapy (aspirin and/or clopidogrel or ticagrelor)
干预措施: Antiplatelet Drug (Drug)
结局指标
主要结局
Montreal Cognitive Assessment (MoCA) Test
时间窗: 6-8 months
次要结局
未报告次要终点
研究者
Hai-Bin Shi
Professor
Nanjing Medical University
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Neurovascular Determinants of Cognitive Function in Adults With Sickle Cell DiseaseSickle Cell DiseaseNCT02946905University of Pittsburgh226
已完成
不适用
Cognitive Dysfunction After Aneurysmal Subarachnoid HaemorrhageCognitive DysfunctionNCT01038193Chinese University of Hong Kong600
招募中
不适用
Vascular function, cognitive impairment and diabetes mellitusDiabetesTCTR20190830001one60
招募中
不适用
Assessing Neurocognition After Cerebrovascular InterventionCarotid Artery DiseasesNeurocognitive DysfunctionNCT03344276University of California, San Diego20
招募中
不适用
Cognitive Decline in Asymptomatic Intracranial Stenosis Patients: A 1-Year Follow-Up StudyMedical TreatmentMagnetic Resonance ImagingAsymptomatic Intracranial StenosisNCT04850001Anhui Medical University40