Effects of tablets containing Lactobacillus salivarius WB21 and hinokitiol on inflammation of gingiva, subjective symptoms in oral cavity, and numbers of bacteria in saliva. - Effects of tablets containing Lactobacillus salivarius WB21 and hinokitiol on oral environment.

Fukuoka Dental College0 个研究点目标入组 24 人开始时间: 2018年8月27日最近更新: 2023年10月17日

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•1. A person diagnosed as suffering from any dental disease by a dentist. 2. Person who underwent periodontal treatment or treatment with antibacterial agent within 3 months prior to the start of the study. 3. Persons who received maintenance such as dental plaque and calculus removal at the dental office within 3 months prior to the start of the test. 4. Smokers. 5. Persons using dentures. 6. Persons who used lactic acid bacteria-containing dentifrice, mouthwash and oral care supplement within 1 month prior to the start of the test. 7. Persons who have a history of systemic diseases such as gastrointestinal disease (gastritis, stomach ulcer, colitis, etc), severe respiratory diseases such as diabetes, liver disease, kidney disease, asthma, severe heart disease, malignant tumor. 8. Milk and hinokitiol allergies. 9. Pregnant or possibly pregnant or breast-feeding. 10. Those who have participated in other clinical trials within one month prior to agree participation or those who intend to participate in other clinical trials after obtaining participation agreement for this study. 11. Persons who judged that the investigator is inappropriate as the subject.

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