To study the effects of meditation on human brain using imaging technique (positron emission tomography) and biochemical markers.
Not Applicable
- Registration Number
- CTRI/2009/091/000727
- Lead Sponsor
- Dr. Raj Kumar YadavAssociate Professor,Department of Physiology,Room No. 2027A,Teaching Block, 2nd Floor,AIIMS, New Delhi-29.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
Group A: Long-term yoga meditator will be enrolled in the study (n=10)
Age:20-60 years
practicing meditation for >5 years
Practicing meditation at least5 days a week,minimumof 20min/session
Group B:The healthy subjects attending one of the courses at Integral Healthy Clinic,Department of Physiology,AIIMS will be recriuted as short termmeditators/ yoga practitioners (n=30)
Group C: Age and sex matched healthy subjects (n=30) noptpracticing any type of yoga/meditation at least for last 2 years.
Exclusion Criteria
EXCLUSION CRITERIA:
Any type of alcoholics and smokers.
History of immunological disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The PET investigation of regional cerebral glucose metabolism(rCMRGlucose) in long-term yoga/meditation practitioners during meditation may show significant increase in the ratio of rCMRGLucose in anterior (frontal areas) to posterior (occipital areas) regions of interest (ROIs) as compared to the baseline PET-CT scan.Timepoint: 3 years
- Secondary Outcome Measures
Name Time Method The effect of yoga on stress management by studying various biochemical markers i.e.cortisol,beta-endorphin, IL-4, IL-6, IL-10, IL-12, TNF-alpha and IFN -gamma may be validated.Timepoint: 3 years