Bordetella Pertussis Carriage in College-aged Students

• Conditions: Carriage of Bordetella Pertussis

• Registration Number: NCT02215564
• Lead Sponsor: University of Virginia

Brief Summary

The objective in this observational cohort study of young adults sampled at three intervals during the academic year is to ascertain if there is carriage of B. pertussis in asymptomatic individuals. We hypothesize that in asymptomatic college students there is no carriage of B. pertussis detectable by polymerase chain reaction (PCR) assay.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-08-06
• Study First Submitted QC: 2014-08-12
• Study First Posted: 2014-08-13
• Study Start: 2014-10
• Status Verified: 2015-05
• Last Update Submitted: 2015-05-27
• Last Update Posted: 2015-05-28
• Primary Completion: 2015-06
• Study Completion: 2015-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Age 18 and above
• Not immunosuppressed
• Not HIV positive (not known to be/self-reported)
• Able to tolerate swab procedures
• Able to provide consent

Exclusion Criteria

• No antimicrobial or immunosuppressive medications taken for chronic conditions

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of participants with B. pertussis by PCR in nasopharyngeal sample at first timepoint	30 minutes	Participants will be tested for B. pertussis by PCR at one visit in October 2014, 30 minutes.

Secondary Outcome Measures

Name	Time	Method
Number of participants with B. pertussis by PCR in nasopharyngeal sample at second timepoint	30 minutes	Participants will be tested for B. pertussis by PCR at one visit in January 2015, 30 minutes.

Trial Locations

Locations (1)

University of Virginia Health System; 🇺🇸 Charlottesville, Virginia, United States