Effect of Statins on Lipid Levels Following the First Acute Coronary Event (MK-0000-204)

Completed

• Conditions: Pure hyperglyceridemia,

• Registration Number: CTRI/2013/02/003429
• Lead Sponsor: Merck Sharp and Dohme

Brief Summary

The current study is proposed to investigate the pattern of dyslipidemia and of lipid treatment practices in patients experiencing first acute cardiovascular event and the extent of residual dyslipidemia after 12 weeks of treatment with statins.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-08-20
• Last Update Posted: 2019-04-28

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 850

Inclusion Criteria

• Currently admitted with a confirmed diagnosis of first acute coronary event (STEMI/NSTEMI/Unstable Angina).
• Access to medical records covering the entire study period, and availability of data required for the study.
• Potential to collect blood sample within 24 hours of onset for symptoms.
• Considered for initiation/maintenance/modification of statin therapy before discharge from hospital.
• Willing to comply with the study requirements.

Exclusion Criteria

Patients who are already participating in a clinical trial or any type of other clinical study involving therapeutic intervention or otherwise failing to consent to interview- Patients with known inherited disorder of lipoprotein metabolism- Patients with history of hypothyroidism, nephrotic syndrome, chronic alcoholism, Cushing syndrome.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total Cholesterol (TC) levels at First Acute Coronary Event	At hospital presentation (Day 1)

Secondary Outcome Measures

Name	Time	Method
Low-Density Lipoprotein Cholesterol (LDLC) levels at First Acute Coronary Event	At hospital presentation (Day 1)

Trial Locations

Locations (20)

Apollo DRDO Hospital; 🇮🇳 Hyderabad, ANDHRA PRADESH, India

Apollo Hospitals; 🇮🇳 Visakhapatnam, ANDHRA PRADESH, India

Apollo Hospitals Educational and Research Foundation (AHERF); 🇮🇳 Chennai, TAMIL NADU, India

Care Hospital Nampally; 🇮🇳 Hyderabad, ANDHRA PRADESH, India

Care Institute of Medical Sciences; 🇮🇳 Ahmadabad, GUJARAT, India

Crosslay Remedies Limited; 🇮🇳 Ghaziabad, UTTAR PRADESH, India

Department of Medicine (Cardiology Division) Vivekananda Institute of Medical Sciences; 🇮🇳 Kolkata, WEST BENGAL, India

Dharamveer Heart Centre; 🇮🇳 Delhi, DELHI, India

Fortis Escorts Hospital; 🇮🇳 Jaipur, RAJASTHAN, India

Fortis Healthcare Limited Escorts Heart Institute & Research Center; 🇮🇳 Delhi, DELHI, India

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Apollo DRDO Hospital

🇮🇳Hyderabad, ANDHRA PRADESH, India

Dr Pramod Kumar Dhar

Principal investigator

9177471112

pramodkumardhar@yahoo.com