Association of COPD Maintenance Medication Adherence With Resource Use and Cost Among COPD Patients-Retrospective Observational Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- AstraZeneca
- 入组人数
- 10,067
- 试验地点
- 1
- 主要终点
- Indicators of COPD control
研究概览
简要总结
The aim of this study is to examine the association of COPD maintenance inhalation medication (Inhaled Corticosteroid or ICS) adherence with COPD exacerbation healthcare resource utilization among COPD patients with exacerbation history.
详细描述
Objectives: The primary objective of this study is to examine the association of COPD maintenance inhalation medication (Inhaled Corticosteroid or ICS) adherence with COPD exacerbation healthcare resource utilization among COPD patients with exacerbation history.
Study design: This study is a retrospective database analysis using 2014-2016 Guangzhou City health insurance database.
Data Source(s): Guangzhou city health insurance database will be used for this study. All outpatient and inpatient visits for one patient during 2014-2016 were available.
Study Population: This study will include patients with a physician COPD diagnosis in Guangzhou city health insurance database during 2015 and with complete treatment data during 1 year before and 1 year after the index date. The rough sample size of the study population was 49,000.
Outcome(s):
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with COPD in 2015;
- •Patients had complete hospital visit data available during pre-index 1 year period and post 1 year follow-up;
- •Patients had at least one COPD exacerbation during 1 year prior to the index date;
- •Patients had at least 2 COPD maintenance medication claims during post index 1 year period, as 2 claims are recommended to calculate adherence.
排除标准
- •Inability to determine diagnoses from claims;
- •Individuals with other chronic respiratory conditions such as respiratory cancer, pulmonary fibrosis, asthma.
结局指标
主要结局
Indicators of COPD control
时间窗: 2015.01-2016.12
Number of exacerbations
Health resource utilization
时间窗: 2015.01-2016.12
Emergency department (ED) visit number
Costs of inpatient treatment
时间窗: 2015.01-2016.12
Cost of all-cause inpatient treatment
次要结局
未报告次要终点