Turning the tide of antimicrobial resistance in intensive care units in Indonesia
Recruiting
- Conditions
- Antimicrobial resistance, Intensive care
- Registration Number
- NL-OMON26918
- Lead Sponsor
- 1.Faculty of Medicine Universitas Indonesia / Dr Cipto Mangunkusumo Hospital Jakarta, Indonesia2. Erasmus MC Rotterdam, The Netherlands
- Brief Summary
The study is published in the journal 'Antimicrobial Resistance and Infection Control'. DOI 10.1186/s13756-017-0296-7.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 550
Inclusion Criteria
All adult patients (age ≥18 years old) admitted to the intensive care unit of Dr Cipto Mangunkusumo Hospital in Jakarta, Indonesia.
Exclusion Criteria
Patients who are discharged within 48 hours from the intensive care unit.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of patients who acquire carriage or infection with A. baumannii with reduced susceptibility to carbapenems, P. aeruginosa with reduced susceptibility to carbapenems, or K. pneumoniae with reduced susceptibility to carbapenems per 100 patient-days at risk in the ICU. <br /><br>An acquisition is defined as a screening culture (throat or rectum) or clinical culture with a first detection of either A. baumannii, P. aeruginosa, or K. pneumoniae, all with reduced susceptibility to a carbapenem, that was not yet present on admission or in the first 48 hours of admission. Thus, for each patient, a maximum of three new acquisition events may occur.
- Secondary Outcome Measures
Name Time Method Measures include quantity and quality of antibiotic usage, the in-ICU crude mortality rate, the hand hygiene compliance of health care workers, and environmental contamination of the above mentioned Gram-negative bacteria with reduced susceptibility to carbapanems.