NCT04068090Unknown不适用
Taxane Induced Peripheral Neuropathy in Chinese Patients With Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2019年8月23日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Total score from the FACT-GOG-Ntx questionnaire
研究概览
简要总结
The purpose of this study is to collect clinical data, blood samples, and self reported symptoms of peripheral neuropathy from Chinese patients with breast cancer after treatment with taxanes. This data will be used to develop predictive markers for neuropathy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Diagnosis of breast cancer
- •Females aged 16 and older
- •Planning to receive or previous treated with taxanes
排除标准
- •Poorly controlled or insulin-dependent diabetes or other condition likely to predispose to neurotoxicity
结局指标
主要结局
Total score from the FACT-GOG-Ntx questionnaire
时间窗: Up to 2 years
Total score from the FACT-GOG-Ntx questionnaire for peripheral neuropathy, ranging from 0-44,higher value represents a worse outcome
次要结局
- Predictive value of genetic variants for the development of neuropathy(In the two weeks before start treatment)
- Total score from the EORTC QLQ - CIPN20 questionnaire(Up to 2 years)
研究者
Ma Fei，MD
Deputy Director
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
研究点 (1)
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