Skip to main content
MedPathMedPath Home
Clinical Trials/NCT04068090
NCT04068090
Unknown
Not Applicable

Taxane Induced Peripheral Neuropathy in Chinese Patients With Breast Cancer

Cancer Institute and Hospital, Chinese Academy of Medical Sciences1 site in 1 country500 target enrollmentAugust 23, 2019
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsBreast Cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Breast Cancer
Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Enrollment
500
Locations
1
Primary Endpoint
Total score from the FACT-GOG-Ntx questionnaire
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study is to collect clinical data, blood samples, and self reported symptoms of peripheral neuropathy from Chinese patients with breast cancer after treatment with taxanes. This data will be used to develop predictive markers for neuropathy.

Registry
clinicaltrials.gov
Start Date
August 23, 2019
End Date
December 2020
Last Updated
6 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ma Fei，MD

Deputy Director

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Eligibility Criteria

Inclusion Criteria

  • •Diagnosis of breast cancer
  • •Females aged 16 and older
  • •Planning to receive or previous treated with taxanes

Exclusion Criteria

  • •Poorly controlled or insulin-dependent diabetes or other condition likely to predispose to neurotoxicity

Outcomes

Primary Outcomes

Total score from the FACT-GOG-Ntx questionnaire

Time Frame: Up to 2 years

Total score from the FACT-GOG-Ntx questionnaire for peripheral neuropathy, ranging from 0-44,higher value represents a worse outcome

Secondary Outcomes

  • Predictive value of genetic variants for the development of neuropathy(In the two weeks before start treatment)
  • Total score from the EORTC QLQ - CIPN20 questionnaire(Up to 2 years)

Study Sites (1)

Loading locations...

Similar Trials

Active, not recruiting
Phase 2
The Effect of Acupuncture on Nerve Pain Caused by Taxane (Chemotherapy) TreatmentBreast CancerTaxane-Induced Peripheral Neuropathy
NCT05458284Memorial Sloan Kettering Cancer Center80
Completed
Not Applicable
Evaluating the Effects of Acupuncture in the Treatment of Taxane Induces Peripheral NeuropathyPeripheral Neuropathy
NCT02831114Prisma Health-Upstate18
Completed
Not Applicable
Early Detection of Taxane-Induced Neuropathy in Women With Breast CancerPeripheral Neuropathy
NCT02549534Indiana University29
Not yet recruiting
Not Applicable
Detection of taxane-induced neuropathy using patient-reported outcomesBreast cancerPeripheral neuropathy
ACTRN12618001378213Royal Adelaide Hospital100
Active, not recruiting
Phase 2
Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast CancerPrognostic Stage IIIC Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage IA Breast Cancer AJCC v8Anatomic Stage IB Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage IIA Breast Cancer AJCC v8Anatomic Stage IIB Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8Anatomic Stage IIIC Breast Cancer AJCC v8Invasive Breast CarcinomaPrognostic Stage I Breast Cancer AJCC v8Prognostic Stage IA Breast Cancer AJCC v8Prognostic Stage IB Breast Cancer AJCC v8Prognostic Stage II Breast Cancer AJCC v8Prognostic Stage IIA Breast Cancer AJCC v8Prognostic Stage IIB Breast Cancer AJCC v8Prognostic Stage III Breast Cancer AJCC v8Prognostic Stage IIIA Breast Cancer AJCC v8Prognostic Stage IIIB Breast Cancer AJCC v8
NCT04001829ECOG-ACRIN Cancer Research Group249