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临床试验/NCT04561141
NCT04561141Unknown不适用

Post Covid Syndrome: Clinical Pattern and Functional Assessment

Assiut University0 个研究点目标入组 85 人开始时间: 2020年12月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
85
主要终点
Identify post covid symptoms

研究概览

简要总结

Aim(s) of the Research :

  1. Identify post covid symptoms
  2. prevalance of post covid syndrome among survivours

详细描述

There is currently very limited information on the nature and prevalence of post-COVID-19 symptoms after hospital discharge. On 11th March 2020, corona virus disease 2019 (COVID-19) was declared a global pandemic by the World Health Organisation (WHO). Egypt has been one of the worst affected countries with over 101,500 confirmed cases and more than 5,696 confirmed deaths at the time of writing (17/9 2020) .1 COVID-19 is caused by the corona virus SARSCoV-2 and presents with a wide spectrum of clinical symptoms. Wu et al reported that 81% of people with COVID-19 in China presented with mild symptoms; 14% presented with symptoms of severe respiratory dysfunction; and 5% developed a critical illness with respiratory failure, septic shock, and multiple organ dysfunction or failure.2 The medium and long-term problems experienced by survivors of COVID-19 after discharge from hospital are currently unknown, but there is some emerging evidence. An Italian study followed-up 143 individuals 7 weeks post-discharge and found 53% reporting fatigue, 43% breathlessness and 27% joint pain.3 Post-discharge symptoms may also be predicted from the previous coronavirus outbreaks of Severe Acute Respiratory Syndrome (SARS) in 2002 and Middle East Respiratory Syndrome (MERS) in 2012. A meta-analysis of 28 follow-up studies found that one quarter of hospitalised survivors of SARS and MERS had reduced lung function and exercise capacity at six months post-discharge.4 At one year, post-traumatic stress disorder (PTSD), depression and anxiety, and reduced quality of life were observed Specific data concerning the rehabilitation needs of this group is therefore urgently required.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients diagnosed as covid 19 with chest ct and/or nasopharyngeal swab for covid 19
  • age 18 years old and above
  • post covid syndrome after 6 weeks

排除标准

  • 1-below age of 18 2 -not confirmed cases
  • symptoms less than 6 weeks

结局指标

主要结局

Identify post covid symptoms

时间窗: after 4 weeks of diagnosis

by interview questionnaire

次要结局

  • prevalance of post covid syndrome among survivours(after 4 weeks of diagnosis)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mostafa Mahmoud

resident doctor

Assiut University

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