Examination of efficacy and safety of PEG-IFN alpha-2a for the treatment of chronic hepatitis B. - PEG-IFN alpha-2a therapy for chronic hepatitis B.

Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine0 sites100 target enrollmentJanuary 4, 2012

Overview

Phase: 未知
Intervention: Not specified
Conditions: chronic hepatitis B
Sponsor: Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine
Enrollment: 100
Status: Recruiting
Last Updated: 2 years ago

No summary available.

Registry

who.int

Start Date

January 4, 2012

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine

•1\.Patient who is administering the sho\-sai\-ko\-to 2\.A patient with the previous history of interstitial pneumonia 3\.Other chronic liver disease patients such as autoimmune hepatitis or alcoholic hepatitis 4\.Patient who has previous history of hypersensitivity for element of PEG\-IFN alpha\-2a or other IFNs 5\.Patient who has previous history of hypersensitivity for biological products such as vaccines 6\.Patient with cirrhosis, liver failure, and liver carcinoma 7\.Hepatic encephalopathy, an esophageal varix, a patient with abdominal dropsy, or a patient with these previous history 8\.A patient with autoimmune diseases (hemolytic anemia, chronic ulcerative colitis, rheumatoid arthritis, etc.), or a patient with these anamneses 9\. Patient who has heart disease difficult to control (cardiac infarction, cardiac failure, and arrhythmia, etc.) 10\. Patient who exists in serious state of mental disease of serious depression, thought of suicide or suicide plan, etc. or with these history 11\. The patient of uncontrollable hypertension 12\. A patient with the past of apoplexy (cerebral infarction, cerebral hemorrhage, subarachnoid bleeding, transient ischemic attack) 13\. Pregnant woman or woman who has possibility of pregnancy or woman while suckling 14\. Additionally, patient judged by doctor that participation in this study is improper