Randomised trial to compare the clinical value of cyclosporin C12 and C2 monitoring after lung transplantation

Papworth Hospital NHS Trust (UK)0 sites90 target enrollmentJuly 8, 2005

Overview

2004 results presented at 24th International Society of Heart and Lung Transplantation https://www.jhltonline.org/article/S1053-2498(03)00838-6/fulltext 2. 2005 results presented at 25th International Society of Heart and Lung Transplantation https://www.jhltonline.org/article/S1053-2498(04)00744-2/fulltext

Registry

who.int

Start Date

July 8, 2005

End Date

April 1, 2006

Last Updated

7 years ago

Study Type

Interventional

Sex

All

Sponsor

Papworth Hospital NHS Trust (UK)

•90 patients lung transplant:
•1\. Adult single or double lung and heart \+ lung transplant recipients (18 years and older)
•2\. Patients receiving Neoral as primary immunosuppression

•1\. Patients not giving voluntary, written informed consent to participate
•2\. Re\-transplantation
•3\. Simultaneous kidney, pancreas, liver or bowel transplantation
•3\. Urine output \<50 ml/hour and/or serum creatinine \=170 mmol/l at the most recent investigation prior to transplantation
•4\. Renal replacement therapy or any form of renal support such as continuous veno\-venous haemofiltration (CVVH) or dialysis before transplantation or within the first post\-operative week
•5\. Patients receiving tacrolimus or sirolimus as primary immuno\-suppression in place of Neoral