Clinical use of L-Arginine as an add on therapy in patients of hypertensio
- Conditions
- Health Condition 1: I10-I16- Hypertensive diseases
- Registration Number
- CTRI/2019/03/018026
- Lead Sponsor
- Pravara Institute Of Medical Sciences Loni
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 180
All the patients of hypertension taking anti- hypertensive drugs since last sixth months
Adult patients between 18-60years
Patients of either gender
Patient ready to give written informed consent and willing to participate in the trial
Patient suffering from Gestational hypertension
Patients suffering from hypertension with Brain disorders
Patients with history of thyroid disorders and taking anti-epileptic medication
Patients on chronic medications other than anti-hypertensive drugs
Use of any drug that may affect nitric oxide synthesis (nitrates, CNS depressant, steroids)
Patients with history of Diabetes mellitus
Renal failure patients
Patient with history of ischemic heart disease, Transient ischemic attack (TIA), Stroke or peripheral arterial disease
Patients with history of recurrent herpes
Patients with history of Cancer treated with radiotherapy or chemotherapy during the last year
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measure changes in systolic blood pressure and Diastolic blood pressure with L-Arginine therapy in hypertensive patients on anti-hypertensive medication.Timepoint: The expected outcome will be measured from Baseline visit i.e on 0day,7thday,14thday and 21thday.
- Secondary Outcome Measures
Name Time Method To measure other clinical,Physiological benefits of add on therapy with L-Arginine in patients of hypertensionTimepoint: After 21 days