Gastric emptying of plant sterol-containing mini drinks in different meal intake scenarios and their effect on gallbladder emptying

Completed

• Conditions: gallbladder motility; gastric emptying; 10017977

• Registration Number: NL-OMON35720
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 24

Inclusion Criteria

• Signed informed consent form
• Sex: male
• Age: 18-55 years
• Body Mass Index (BMI): 20-30 kg/m2

Exclusion Criteria

• History of severe cardiovascular, respiratory, urogenital, gastrointestinal/ hepatic, hematological/immunologic, HEENT (head, ears, eyes, nose, throat), dermatological/connective tissue, musculoskeletal, metabolic/nutritional, endocrine, neurological/psychiatric diseases, allergy, major surgery which might limit participation in or completion of the study protocol.
• Use of any medication on regular basis.
• Use of paracetamol prior to treatment (<= 48 hour).
• Use of plant sterol/stanol enriched products or supplements.
• Blood donations less than three months previous to study enrolment.
• Known hypersensitivity or allergy towards paracetamol.
• Hyperlipidaedimia (TG > 3 mmol/L and/or tot. chol. > 8 mmol/L)
• Corn products prior to treatment (<= 48 hour)
• Presence of gallbladder stones

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary study parameters are gastric emptying and gallbladder volume.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are plasma CCK, plant sterol concentrations.</p><br>