To study the ocular perfusion pressure between two general anaesthesia maintenance protocols in adults scheduled for elective thoracolumbar spine surgeries.
Phase 4
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/08/056268
- Lead Sponsor
- Gargi A V
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 52
Inclusion Criteria
1. ASA PS 1 and 2
2. Scheduled for elective thoracolumbar spine surgeries in prone position.
Exclusion Criteria
1. Uncontrolled hypertension
2. Uncontrolled Diabetes mellitus
3. History of allergic reactions to any drugs used in the study.
4. Baseline IOP > 30 millimeters of mercury
5. Significant prone provocative test.
6. Pre-existing glaucomatous cupping.
7. Pre-existing primary-angle closure glaucoma.
8. Previous eye surgeries.
9. Previous eye disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare ocular perfusion pressure at predetermined time points perioperatively between two groups of patients receiving either propofol or desflurane for the maintenance of anesthesia during elective thoracolumbar spine surgeries in prone position.Timepoint: Five minutes after extubation. <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1. To compare mean arterial pressure(MAP) at predetermined time points between two groups of patients. <br/ ><br>2. To compare the number of hypotensive episodes between the two groups of patients(defined as MAP 65 mm Hg for more than 5 minutes intraoperatively)Timepoint: Thirty minutes after extubation.