Comparison Between Turquoise and Blue Light in Treatment of Neonatal Jaundice Using Light Emission Diodes

Not Applicable

Completed

• Conditions: Uncomplicated Neonatal Hyperbilirubinemia
• Interventions: Other: Phototherapy

• Registration Number: NCT02154165
• Lead Sponsor: University of Aarhus

Brief Summary

The optimal wavelength for phototherapy for neonatal jaundice remains to be clarified by clinical studies. Previous iv vivo studies have shown that turquoise light at wavelength about 490 nm is more efficacious than blue light at wavelength 460 nm, which is the golden standard in phototherapy treatment today. Though, previous studies used light tubes, today we use light emitting diodes (LED'S).

The overall aim of this study was therefore to compare the efficacy of turquoise LED's versus blue LED's for decreasing total serum bilirubin in neonates with gestational age \> 33 weeks and uncomplicated hyperbilirubinemia.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01
• Primary Completion: 2013-12
• Study Completion: 2013-12
• Status Verified: 2014-05
• Study First Submitted: 2014-05-30
• Study First Submitted QC: 2014-06-02
• Last Update Submitted: 2014-06-02
• Study First Posted: 2014-06-03
• Last Update Posted: 2014-06-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Newborns with gestational age >33 weeks and neonatal hyperbilirubinemia requiring treatment with phototherapy according to the national guidelines

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Exclusion Criteria

• Haemolytic disease (Rhesus and Kell blood type isoimmunization, spherocytosis)
• Liver disease

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Blue light wavelenght 460 nm	Phototherapy	-
Turquoise light wavelength 499 nm	Phototherapy	-

Primary Outcome Measures

Name	Time	Method
Decrease in total serum bilirubin	24 hours	The infants were treated with phototherapy for 24 hours, which is the standard treatment.

Trial Locations

Locations (1)

Neonatal department, Aalborg University Hospital; 🇩🇰 Aalborg, Denmark