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Clinical Trials/IRCT20230614058480N1
IRCT20230614058480N1
Recruiting
Phase 3

Comparing the synergistic effect of Combination of curcumin and piperine supplementation as an adjuvant treatment to the usual treatment method using Bevacizumab in patients with neovascular age-related macular degeneration

Zahedan University of Medical Sciences0 sites30 target enrollmentTBD
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Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Not specified
Sponsor
Zahedan University of Medical Sciences
Enrollment
30
Status
Recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Zahedan University of Medical Sciences

Eligibility Criteria

Inclusion Criteria

  • •Signed written informed consent
  • •Age 45 \- 80 years, male or female
  • •Neovascular AMD is diagnosed with active lesions

Exclusion Criteria

  • •Any history of allergy or sensitivity to turmeric, pepper, curcumin or piperine
  • •Any history of allergy or sensitivity to antiVGEFs
  • •With vitreous hemorrhage in the studied eyes
  • •With geographic atrophy, epiretinal membrane or hard subfoveal exudates involving the foveal in the studied eyes
  • •With opacification of the refractive medium (such as apparent cataract) or pupillary constriction that significantly interferes with vision testing or evaluation of the anterior segment and fundus in the study eyes.
  • •With rhegmatogenous retinal detachment, macular hole, or choroidal neovascularization (CNV) of any cause other than AMD (eg, fundus angioid streaks, ocular histoplasmosis, pathologic myopia, trauma) in study eyes.
  • •With apparent afferent pupillary defect (RAPD) in the studied eyes
  • •With polypoidal choroidal vasculopathy (PCV) or retinal angiomatous proliferation (PAP) in the studied eyes
  • •With intraocular pressure above 25 mmHg despite treatment
  • •With active inflammation in each eye, such as conjunctivitis, keratitis, scleritis, blepharitis, endophthalmitis, and uveitis.

Outcomes

Primary Outcomes

Not specified

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