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Clinical Trials/NCT05562011
NCT05562011
Terminated
Not Applicable

A Pilot Feasibility Study of an Ambulatory Multi-Vital Signs Monitor in Perioperative Patients

Wake Forest University Health Sciences1 site in 1 country61 target enrollmentAugust 18, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Perioperative/Postoperative Complications
Sponsor
Wake Forest University Health Sciences
Enrollment
61
Locations
1
Primary Endpoint
Preoperative Caretaker Monitor Placement Success
Status
Terminated
Last Updated
2 years ago

Overview

Brief Summary

The purpose of this research is evaluate vital signs (VS), which include non-invasive blood pressure, pulse rate, respiratory rate and Oxygen Saturation (SpO2) using a portable wrist monitoring device called a Caretaker. This device has been cleared by the Food and Drug Administration (FDA) for use and allows the study team to check vital signs in a participant's normal setting.

Participation in this study will involve wearing this portable device at 2 different time points:

  1. for up to 24 hours immediately during and after the participant's preoperative visit to obtain baseline vital signs during normal activity and during sleep and
  2. after surgery up to 24 hours while participant recovers prior to discharge from the hospital

Detailed Description

Anesthesiologists and surgeons examine vital signs such as heart rate (HR), respiratory rate (RR), oxygen saturation (SaO2) and blood pressure (BP) in an effort to detect extremes of altered VS and remediate these alterations prior to surgery and anesthesia. In most preoperative clinics, however, these VS are measured once and no further assessments are made until they arrive for their surgery. Patients with cardiac and pulmonary disease, however, can have highly variable VS. The Caretaker device is a wrist device designed to measure relatively continuous VS over a period up to 24 hours. The device is accompanied by a finger cuff that measure pulse and respiratory rate, along with a non-invasive blood pressure detector and pulse oximeter. In an effort to detect VS that may not be recognized with the usual one-time measurement in the clinic, the study team plans to monitor ambulatory preoperative VS in patients who meet the study criteria, for up to 16-24 hours preoperatively. They will then return their device on the day of surgery. Postoperatively, the study team will place a CareTaker device once again and measure these same VS in the same patients for up to 24 hours prior to discharge.

Registry
clinicaltrials.gov
Start Date
August 18, 2021
End Date
October 24, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Preoperative Caretaker Monitor Placement Success

Time Frame: Baseline

Number of participants who had the presence of (data existing for at least 70% of 5-minute time periods) for all of the vital signs of interest together--heart rate (HR), blood pressure (BP), respiratory rate (RR), arterial oxygen saturation (SaO2) after placement of the device on the subject's wrist and hand.

Caretaker Data Capture Rate

Time Frame: Post-Op Hour 24

Number of participants with no missing values expressed

Ease of Use Determined by Number of Participants With Sleep or Activities of Daily Living (ADLs) Interference

Time Frame: Pre-Op Hour 24

Participants' description of ease of use (interfered with Activities of Daily Living (ADLs) or sleep) in Yes/No format. Data will be collected to demonstrate percent of patients who answered "Yes" to Sleep or ADL interference. Free text will also be recorded for qualitative purposes. Shows Caretaker Feasibility.

Postoperative Caretaker Healthcare Provider (HCP) Usability

Time Frame: Post-Op Hour 24

Using postoperative nurse verbal feedback on usability of the Caretaker monitor on subjects scheduled for surgery during the perioperative period. Percent of nurses who answer yes to the question: Did you have any difficulty using the Caretaker monitor?

Monitor Return Rate

Time Frame: Baseline through Pre-Op Hour 24

Percent of monitors returned to our research technicians

Secondary Outcomes

  • Heart Rate--percent of Time Parameters(Pre-Op Hour 24, Post-Op Hour 24)
  • Respiratory Rate(Pre-Op hour 24, Post-Op Hour 24)
  • SaO2--Percent of Time(Pre-Op Hour 24, Post-Op Hour 24)
  • Non-Invasive Mean Arterial Blood Pressure (MBP)(Pre-Op Hour 24, Post-Op Hour 24)
  • Non-Invasive Diastolic Blood Pressure (DBP)(Pre-Op Hour 24, Post-Op Hour 24)
  • Arterial Oxygen Saturation (SaO2)(Post-Op Hour 24)
  • Non-Invasive Systolic Blood Pressure (SBP)(Pre-Op Hour 24, Post-Op Hour 24)
  • Non-Invasive Blood Pressure--MBP Percent of Time Parameters(Pre-Op Hour 24, Post-Op Hour 24)
  • Number of Rapid Response Team Calls(During hospitalization up to Postoperative Day 30)
  • Heart Rate(Pre-Op hour 24, Post-Op Hour 24)
  • Respiratory Rate--Percent of Time Parameters(Pre-Op hour 24, Post-Op Hour 24)
  • Mortality Rate(Day 30)
  • Average Length of Hospital Stay(Up to Postoperative Day 30)
  • ICU Transfer Rate(Up to Postoperative Day 30)

Study Sites (1)

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