Study of the Effect of Lactisole on the Intestinal Glucose Uptake
Phase 1
Completed
- Conditions
- Healthy
- Interventions
- Dietary Supplement: lactisoleOther: placebo
- Registration Number
- NCT00631293
- Lead Sponsor
- University Ghent
- Brief Summary
Study of the effect of lactisole on glucose uptake
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 10
Inclusion Criteria
- Male subject, between 18 and 50 years
- General good health condition
Exclusion Criteria
- Overweight (Body Mass Index ≥30)
- Metabolic disorders
- History of gastrointestinal disorders
- Regular (daily) intake of medication
- Smoking more than 10 cigarettes/day
- History of drug abuse
- Exhaustive (> 3 units/day) alcohol consumption
- Exhaustive (> 5 units/day) caffeine consumption (coffee, tea, cola, or other caffeine based drinks)
- Recent (in the last 14 days) donation of blood
- Recent (in the last 2 days) donation of blood plasma
- Participation in another trial within 4 weeks before the start of the study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description 1 lactisole administration of lactisole 2 placebo administration of placebo
- Primary Outcome Measures
Name Time Method Differences in glucose uptake rate in lactisole treated subjects versus placebo treated subjects during oral glucose tolerance test 5 weeks
- Secondary Outcome Measures
Name Time Method Differences in blood insulin, glucagon, triglycerides, GIP and GLP-1 in lactisole treated subjects versus placebo treated subjects during oral glucose tolerance test, ECG 5 weeks
Trial Locations
- Locations (1)
University Hospital Ghent
🇧🇪Ghent, Belgium