MedPath

LARS for Chinese Patients

Completed
Conditions
Incidence and Risk Factors of Low Anterior Resection Syndrome
Registration Number
NCT05373602
Lead Sponsor
Third Affiliated Hospital, Sun Yat-Sen University
Brief Summary

Low anterior resection syndrome (LARS) frequently occurs in patients undergoing low anterior resection (LAR). However, the incidence, exact mechanism and risk factors of major LARS largely variate in different studies. Considering varieties and differences of patient characteristics between Chinese patients and the western ones, this retrospective study aims to investigate the incidence of LARS in Chinese patients undergoing laparoscopic LAR, and to explore perioperative risk factors that might be associated with major LARS. Consequent patients undergoing laparoscopic LAR and free from disease recurrence from January 2015 to May 2021 were issued with LARS questionnaire. Incidence of LARS and patient data were collected and analyzed.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
261
Inclusion Criteria

Patients diagnosed as rectal cancer and underwent radical laparoscopic LAR and straight colorectal/coloanal anastomosis (with or without a protective stoma) by a same surgical team

Exclusion Criteria

either local or distal recurrence, severe complications such as postoperative anastomotic leakage, failure of protective stoma closure, data missed and no responding to LARS questionnaire

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
incidence of major LARSat least 1 months postoperatively

incidence of major Low Anterior Resection Syndrome

incidence of LARSat least 1 months postoperatively

incidence of Low Anterior Resection Syndrome

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

the Third Affiliated Hospital of Sun Yat-Sen University

🇨🇳

Guangzhou, Guangdong, China

© Copyright 2025. All Rights Reserved by MedPath