IRCT20090117001556N147
Not yet recruiting
Phase 2
Evaluating the effectiveness of citalopram and sertraline in the treatment of depression with respect to the level of BDNF, IL-6, and cortisol in men and women with major depressive disorder: A randomized double-blinded clinical trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Tehran University of Medical Sciences
- Enrollment
- 80
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age between 18\-60 years old
- •Based on DSM\-V have a diagnosis of major depression (MDD) and their minimum severity of depression based on HDRS is 19
Exclusion Criteria
- •Any other mental disorder in another axis
- •Serious suicidal thoughts (\<2 in suicidal HDRS section)
- •History of ECT in recent two months
- •History of mania and hypomania
- •Thyroid dysfunctions
- •History of cardiovascular disease
- •Autoimmune disorders
- •Presence of active infection
- •Neurologic disorders like epilepsy and Alzheimer's disease
- •Liver disease
Outcomes
Primary Outcomes
Not specified
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