NL-OMON52908招募中不适用
COLLISION-XL trial: Unresectable colorectal liver metastases: stereotactic body radiotherapy versus microwave ablation - a phase II prospective randomized controlled trial for CRLM 3-5 cm - COLLISION XL - SBRT vs MWA for unresectable CRLM 3-5 cm
Radiologie en nucleaire geneeskunde0 个研究点目标入组 68 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 68
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Histological documentation of primary colorectal tumour;
- •1-3 unresectable CRLM size 3-5 cm eligible for both MWA and SBRT (target
- •Additional unresectable CRLM < 3 cm should be ablatable;
- •Additional unablatable CRLM should be resectable;
- •No or limited extrahepatic disease (1 extrahepatic lesion is allowed, not
- •including positive para-aortal lymph nodes, celiac lymph nodes, adrenal
- •metastases, pleural carcinomatosis or peritoneal carcinomatosis);
- •Maximum number of total CRLM is 5 if there is extrahepatic disease and 10 if
- •there is no extrahepatic disease;
- •Unsuitable for (further) chemotherapy regimens
- •Resection for resectable lesions considered possible obtaining negative
- •resection margins (R0) and preserving adequate liver reserve
- •Previous radiotherapy, surgical resection or focal ablative therapy for CRLM
- •prior to inclusion are allowed;
- •Age >18 years;
- •Written informed consent
排除标准
- •Pregnant or breast-feeding subjects;
- •Immunotherapy <= 6 weeks prior to the procedure;
- •Chemotherapy <= 6 weeks prior to the procedure;
- •Severe allergy to contrast media not controlled with premedication;
研究者
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