IRCT20160516027929N7
Completed
N/A
Comparison of the Efficacy of High-Flow Nasal Oxygen Therapy and Noninvasive Ventilation in patients with COPD Exacerbation
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Chronic obstructive pulmonary disease (COPD).
- Sponsor
- Shahid Beheshti University of Medical Sciences
- Enrollment
- 68
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •The presence of chronic obstructive pulmonary disease (COPD) and acute respiratory failure
- •pH \< 7\.35
- •Arterial pressure of carbon dioxide (PaCO2\) equal to or greater than 45mmHg
Exclusion Criteria
- •\- Mechanical ventilation in the past 60 days (using any non\-invasive ventilation or high blood oxygen through the nasal cannula (HFNT) prior to enrollment in the study and after the onset of acute upper respiratory failure (AHRF)
- •\- Non\-invasive ventilation for home care
- •\- Undesirable clinical condition (require a vasopressor for\> 24 hours, acute coronary syndrome or life\-threatening arrhythmias (
- •\- Refusal of treatment
- •\- Disorder in more than two organs
- •\-Heart failure
- •\- The respiratory tract requires a tracheal intubation
- •\- Trauma or burn in the neck and face
- •\- Pregnancy
- •\- Refusal of consent
Outcomes
Primary Outcomes
Not specified
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