German Childhood Glaucoma Registry - Substudy
- Conditions
- Q15.0Q12.0Congenital glaucomaCongenital cataract
- Registration Number
- DRKS00031227
- Lead Sponsor
- Augenklinik und Poliklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Presence of one of the following diagnoses:
a) primary congenital glaucoma (PCG)
b) juvenile open-angle glaucoma (JOAG)
c) secondary glaucoma following lentectomy (aphakic glaucoma)
d) secondary glaucoma due to anterior segment dysgenesis
e) cataract (control group)
- no previous surgery (except from lentectomy in case of aphakic glaucoma)
- no other ocular or systemic pathologies
- inclusion into the German Childhood Glaucoma Registry (ReCG) and additional informed consent of caregivers for substudy
- language barrier
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in proteomic composition of aqueous humor (AH) in children with glaucoma compared to a control group (children with cataract) examined by liquid chromatography-mass spectrometry (LC-MS) prior to glaucoma or cataract surgery
- Secondary Outcome Measures
Name Time Method - Influence of clinical parameters such as intraocular pressure, corneal diameter, axial length, central corneal thickness, corneal findings, gonioscopic findings, funduscopic findings <br>- Influence of genetic mutations (if available)
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.