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Clinical Trials/ISRCTN56283883
ISRCTN56283883
Completed
N/A

Early detection and psychological intervention for individuals at high risk of psychosis 2

niversity of Manchester (UK)0 sites320 target enrollmentAugust 29, 2008
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Overview

Phase
N/A
Intervention
Not specified
Conditions
Not specified
Sponsor
niversity of Manchester (UK)
Enrollment
320
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
August 29, 2008
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity of Manchester (UK)

Eligibility Criteria

Inclusion Criteria

  • •Trial entry criteria will be assessed using the Comprehensive Assessment of At\-Risk Mental States (CAARMS). Patents must satisfy one of the following to be eligible for inclusion into this study:
  • •1\. Brief limited intermittent psychotic symptoms (BLIPS) defined as a score of 6 on any positive item, with symptoms lasting less than one week and resolving without antipsychotic medication
  • •2\. Attenuated symptoms (AS), defined as the presence of positive symptoms that score 3\-5 and have begun in the last year and which occur at least once per week in the last month
  • •3\. State\-plus\-trait group (SPT), operationally defined by the presence of an at\-risk mental state (recent deterioration in function of 30 points or more on the Global Assessment of Functioning) plus either a family history indicated by a first degree relative with a history of any psychotic disorder or a diagnosis of schizotypal personality disorder in the participant
  • •In addition, the patient must fulfil both of the following:
  • •4\. Age 14\-35
  • •5\. Seeking help for symptoms (the latter criterion is necessary to ensure that the provision of treatment to the participants is ethical)

Exclusion Criteria

  • •1\. Current or previous receipt of antipsychotic medication for more than two days
  • •2\. Moderate to severe learning disability
  • •3\. Organic impairment
  • •4\. Non\-English speaking (since this would prevent the use of standardised assessment instruments)

Outcomes

Primary Outcomes

Not specified

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