Whiplash Associated Disorders - Sensory Changes During Rehabilitation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- Changes in Pressure Pain Thresholds
研究概览
简要总结
This study investigates the sensory profile of people suffering from whiplash associated disorders (WAD) during rehabilitation.
详细描述
Altered pain sensitivity is commonly reported in WAD populations when compared to a healthy control group but how/if this changes over time during rehabilitation is unclear. This study investigates the effect of 2 weeks rehabilitation protocol on pain sensitivity in a group suffering from WAD compared to a healthy control group.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •No more than 3 weeks since MVA/WAD
- •WAD grade II defined by Quebec Task Force classification
- •Controls • Being healthy and free from any pain specific to the low back and/or in general
排除标准
- •Applies for both groups:
- •Pain related to a specific pathology such as spinal stenosis, metastasis, fracture, nerve lesions or injuries to the brain etc.
- •Previous painful condition (including neck pain) in the previous 6 months.
- •Prior surgery in the neck or shoulder area.
- •Radiculopathy.
- •Multiple painful sites/areas unrelated to the neck pain.
- •Operation to the spine.
- •Any neurological or systemic diseases which can affect the outcome measures.
- •Pregnancy.
- •Lack of ability to cooperate.
- •Additional exclusion criteria for Controls:
- •No current or previous history of on-going pain, defined as pain in the neck/shoulder region and/or elsewhere during the past 6 months.
结局指标
主要结局
Changes in Pressure Pain Thresholds
时间窗: Baseline, 2 weeks, 6 months
Changes in pressure pain thresholds will be determined with pressure algometry bilaterally over the neck and leg. PPT is defined as the exact time point where the pressure is first being perceived at painful.
Changes in Conditioned Pain Modulation
时间窗: Baseline, 2 weeks, 6 months
Changes in condition pain modulation (CPM) will be measures by recording PPT bilaterally over the neck and leg prior to and following a painful stimuli (a pressure cuff is inflated around the upper arm to create the conditioned stimulus). CPM value is calculated by subtracting raw PPT (without painful stimuli) from PPT under the conditioned stimulus.
次要结局
- Neck Disability Index (NDI)(Baseline, 2 weeks, 6 months)