Evaluation of Antimicrobial Efficacy of Green Tea, Garlic With Lime, Pomegranate Extract and Chlorhexidine Mouth Rinses in a Group of Egyptian Children (In-Vivo Study)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 84
- 试验地点
- 1
- 主要终点
- patient satisfaction
研究概览
简要总结
the aim of the clinical trial is to evaluate the antimicrobial efficacy of the herbal mouth rinses against chlorhexidine mouth rinse.
详细描述
The present study was carried out on 84 children. Children were recruited based on certain inclusion criteria after signing a written informed consent by their parents. They were divided into 4 groups. Group (I) the children rinsed with Chlorhexidine mouth rinse, the child rinsed for 1 minute and plaque samples were collected from the child before and after rinsing. Group (II) children rinsed with green tea extract, while group (III) children rinsed with garlic with lime extract and group (IV) the children rinsed with pomegranate extract mouth rinse with the same procedures. .child satisfaction was measured using 5-point pictorial likert scale which is graded from 1 to 5 (1.Excellent.2.Good.3 Average 4.Poor. 5. Very poor).
All the plaque samples were collected and put in sterile test tubes containing thioglycolate as a transport media. They transferred to the microbiology laboratory within half an hour after rinsing for detection of bacterial counts. These samples were incubated 48-96 hours at 37°C. Number of bacterial colonies were counted by hand-held digital colony counter.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
the participant didn't know what he rinsed with the prescribed group of mouth rinse.
the outcome assessor didn't know what group of mouth rinse belong to the bacterial count that was evaluated.
入排标准
- 年龄范围
- 5 Years 至 8 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 5-8 years.
- •No history of systemic disease.
- •Patients didn't received antibiotics for at least 3 months before and during the study
排除标准
- •Children who can't expectorate completely or brush their teeth on their own.
- •Fixed or removable orthodontic appliances.
- •Children with intra oral abscess, oral lesions or gingival diseases.
- •Parental consent was not acquired
研究组 & 干预措施
Pomegranate extract mouth rinse
pomegranate extract
干预措施: Pomegranate extract mouth rinse (Procedure)
Green tea extract mouth rinse
group green tea extract
干预措施: Green tea extract mouth rinse (Procedure)
Garlic with lime extract mouth rinse
garlic with lime extract
干预措施: Garlic with lime extract mouth rinse (Procedure)
Chlorhexidine mouth rinse
chlorhexidine
干预措施: Chlorhexidine mouth rinse (Procedure)
结局指标
主要结局
patient satisfaction
时间窗: Through study completion, an average of 1 month
Child satisfaction was measured using a 5-point pictorial likert scale .This Facial image scale was suitable and easy way to evaluate patient satisfaction about taste, smell and willing to use the mouth rinse. Its format was graded from 1 to 5 while 1 is the most satisfied and 5 is the least satisfied
次要结局
- bacterial count(1 day after rinsing)
研究者
omnia sayed
Principal investigator and demonstrator at Pediatric Dentistry & Dental Public Health Department
Ain Shams University
