A Comparative Study Between Ultrasound-guided Thoracic Paravertebral Block, Pectoral Nerves Block, and Erector Spinae Block for Pain Management in Cancer Breast Surgeries. A Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- The primary outcome of the study will be duration of analgesia (time to first rescue analgesia after administration of the block).
研究概览
简要总结
Aim of the work The aim of the study is to compare between the effects of ultrasound guided thoracic paravertebral block, pectoral nerve block II, and erector spinae block in management of pain during cancer breast surgeries. The hypothesis of the study is that the three groups will give comparative results.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •ASA physical status classification class I or II
- •Age group 18 - 60 years of the female gender
- •Patients undergoing breast cancer surgeries
排除标准
- •Patient refusal
- •History of hypersensitivity to local anesthetics
- •Bleeding disorders or patients receiving anticoagulants
- •Spine or chest wall deformities
- •Local infection at the site of injection.
研究组 & 干预措施
Erector spinae block Group (C)
Will receive erector spinae block
干预措施: IV morphine (Drug)
Paravertebral block Group (A)
Will receive thoracic paravertebral block
干预措施: Ultrasound guided block (Procedure)
Control Group (D)
Patient will receive opioid only for management of their perioperative pain
干预措施: IV morphine (Drug)
Paravertebral block Group (A)
Will receive thoracic paravertebral block
干预措施: IV morphine (Drug)
Pectoral block Group (B)
Will receive pectoral 1 and 2 block
干预措施: Ultrasound guided block (Procedure)
Pectoral block Group (B)
Will receive pectoral 1 and 2 block
干预措施: IV morphine (Drug)
Erector spinae block Group (C)
Will receive erector spinae block
干预措施: Ultrasound guided block (Procedure)
结局指标
主要结局
The primary outcome of the study will be duration of analgesia (time to first rescue analgesia after administration of the block).
时间窗: 0-24o minutess
minutes
次要结局
- Postoperative nausea and vomiting (PONV)(48 hours)
- Postoperative pain(48 hours)
- Total morphine consumption(48 hours)
研究者
kareem Mikhamer
Assistant fellow
Menoufia University