Skip to main content
Clinical Trials/NCT05076773
NCT05076773
Completed
N/A

A Comparative Study Between Ultrasound-guided Thoracic Paravertebral Block, Pectoral Nerves Block, and Erector Spinae Block for Pain Management in Cancer Breast Surgeries. A Randomized Controlled Study

Menoufia University1 site in 1 country80 target enrollmentApril 10, 2019

Overview

Phase
N/A
Intervention
IV morphine
Conditions
Pain, Postoperative
Sponsor
Menoufia University
Enrollment
80
Locations
1
Primary Endpoint
The primary outcome of the study will be duration of analgesia (time to first rescue analgesia after administration of the block).
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Aim of the work The aim of the study is to compare between the effects of ultrasound guided thoracic paravertebral block, pectoral nerve block II, and erector spinae block in management of pain during cancer breast surgeries. The hypothesis of the study is that the three groups will give comparative results.

Registry
clinicaltrials.gov
Start Date
April 10, 2019
End Date
August 10, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

kareem Mikhamer

Assistant fellow

Menoufia University

Eligibility Criteria

Inclusion Criteria

  • ASA physical status classification class I or II
  • Age group 18 - 60 years of the female gender
  • Patients undergoing breast cancer surgeries

Exclusion Criteria

  • Patient refusal
  • History of hypersensitivity to local anesthetics
  • Bleeding disorders or patients receiving anticoagulants
  • Spine or chest wall deformities
  • Local infection at the site of injection.

Arms & Interventions

Erector spinae block Group (C)

Will receive erector spinae block

Intervention: IV morphine

Paravertebral block Group (A)

Will receive thoracic paravertebral block

Intervention: Ultrasound guided block

Control Group (D)

Patient will receive opioid only for management of their perioperative pain

Intervention: IV morphine

Paravertebral block Group (A)

Will receive thoracic paravertebral block

Intervention: IV morphine

Pectoral block Group (B)

Will receive pectoral 1 and 2 block

Intervention: Ultrasound guided block

Pectoral block Group (B)

Will receive pectoral 1 and 2 block

Intervention: IV morphine

Erector spinae block Group (C)

Will receive erector spinae block

Intervention: Ultrasound guided block

Outcomes

Primary Outcomes

The primary outcome of the study will be duration of analgesia (time to first rescue analgesia after administration of the block).

Time Frame: 0-24o minutess

minutes

Secondary Outcomes

  • Postoperative nausea and vomiting (PONV)(48 hours)
  • Postoperative pain(48 hours)
  • Total morphine consumption(48 hours)

Study Sites (1)

Loading locations...

Similar Trials