A Clinical Study to Determine Association of Serum Vitamin D and Serum Prolactin with Uterine Fibroid in Indian Population

Asheesh Sachdeva0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•Inclusion Criteria for cases
•1.Female subjects with 18 to 50 years of age (both inclusive) who are in perimenopausal status.
•2.Documented evidence of atleast one uterine fibroid lesion of 2 cm3 or greater on ultrasonography.
•3.Ability to provide consent.
•Inclusion Criteria for control
•1.Female subjects with 18 to 50 years of age (both inclusive) who are in pre-menopausal status.
•2.Documented evidence of no uterine fibroid lesion on ultrasonography.
•3.Ability to provide consent.

•1.Pregnant and lactating women
•2.Women with a history of abortion or miscarriage in last 6 months
•3.Women with history of prior surgery for fibroids (myomectomy) or hysterectomy
•4.Women with concomitant use of vitamin D supplements or history of vitamin D supplement within last 3 months
•5.Women with concomitant use of hormonal treatment (including oral contraceptives) or history of hormonal treatment within last 3 months
•6.Women with concomitant use of drug known to increase the serum prolactin levels [e.g., haloperidol, chlorpromazine, thioridazine, thiothixene (typical antipsychotics); risperidone, amisulpride, molindone, zotepine (atypical antipsychotics); sertraline, fluoxetine, paroxetine, pargyline, clorgyline (antidepressants); buspirone, alprazolam (psychotropics); metoclopramide and domperidone (prokinetics), alpha-methyldopa, reserpine and verapamil (antihypertensive), morphine (opiates)]
•7.Women with diabetes mellitus, pituitary and hypothyroidism, chronic renal failure, or psychiatric disease

发起方

Asheesh Sachdeva