Comparison of two drugs (Dexmedetomidine and Fentanyl) which are used in epidural anaesthesia for lower limb surgery.
Not Applicable
Completed
- Registration Number
- CTRI/2019/02/017400
- Lead Sponsor
- Department of Anaesthesia SSG Hospital Vadodara
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
American Society of Anaesthesiologist (ASA) Grade I and II, Patients scheduled for elective lower limb orthopaedic surgery (Unilateral or bilateral tibia and fibula surgeries like internal fixation , external fixation and plating).
Exclusion Criteria
1.Patientsâ?? refusal/unable to give consent.
2.Patients with ASA status III and IV.
3.Patients with allergy to amide local anaesthetics .
4.Patients on α 2 antagonists, ACE inhibitors and
calcium channel blockers, B blockers.
5.Patients with ischemic heart disease, heart block, Dysrhythmias.
6.Pregnant patients and Morbid obesity (BMI >35 kg/square meter).
7.Patients with Coagulopathy, Renal and liver impairment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to onset of anaesthesia at T 10 dermatomal level (min)Timepoint: 7 min
- Secondary Outcome Measures
Name Time Method To document duration of effective analgesia, to find out Level of sedation,to find out adverse effects.Timepoint: 1,5,10 upto 24 hrs