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临床试验/NCT05722665
NCT05722665已完成不适用

The Predictive Capacity of a Convolutional Neural Network (CNN) Model to Detect Viral Pneumonia in Adult Patients With Coronavirus Disease 2019 (COVID-19) in Cali, Colombia

Fundacion Clinica Valle del Lili1 个研究点 分布在 1 个国家目标入组 3,599 人开始时间: 2021年8月26日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
3,599
试验地点
1
主要终点
COVID-19 (coronavirus disease 2019) pneumonia chest radiograph identified

研究概览

简要总结

This study aims to design a Convolutional Neural Network (CNN) and apply an attention model to help differentiate pneumonia due to Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pneumonia due to other viruses/bacteria, and normal chest x-ray (CXR) in clinical practice. A bank of digital chest images from a high-complexity health facility in Cali, Colombia, was used.

详细描述

To differentiate coronavirus disease 2019 (COVID-19) pneumonia from other types of pneumonia, expert radiologists must analyze the chest x-ray (CXR) to identify visual, radiographic patterns associated with Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. It is challenging because the findings are similar for different types of pneumonia.

Since the manual diagnosis of COVID-19 from CXR is a difficult and time-consuming process, applying deep learning (DL) models to medical image analysis is a current hot research topic. This work will develop a new Convolutional Neural Network (CNN) to detect COVID-19 radiographs. It will use a large dataset of chest radiographs classified into three classes: viral/bacterial pneumonia, COVID-19 pneumonia, and normal images. The study aims to incorporate a new attention module that applies CNNs to the linear projection operation to help differentiate COVID-19 pneumonia from other pneumonia and normal chest radiographs in clinical practice.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Chest radiographs from patients without COVID-19 or other pneumonia took before the pandemic start date (January 2020)
  • Chest radiographs from patients with COVID-19 confirmed by positive Reverse Transcriptase polymerase chain reaction (RT-PCR) and/or presence of antibodies to COVID-19 and/or positive COVID-19 viral antigen.
  • Chest radiographs from patients without COVID-19 confirmed by a negative Reverse Transcriptase polymerase chain reaction (RT-PCR) and other pneumonia diagnoses taken before the pandemic start date (January 2020)

排除标准

  • 未提供

结局指标

主要结局

COVID-19 (coronavirus disease 2019) pneumonia chest radiograph identified

时间窗: month 8

Development and determination of the predictive capacity of a Convolutional Neural Network model to detect viral pneumonia in chest radiographs of adult patients with acute respiratory disease secondary to SARS-COV-2 infection.

次要结局

未报告次要终点

研究者

发起方
Fundacion Clinica Valle del Lili
申办方类型
Other
责任方
Sponsor

研究点 (1)

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