Effect of cataract surgery on cornea.

Not yet recruiting

• Conditions: Age-related incipient cataract, (2) ICD-10 Condition: H250||Age-related incipient cataract,

• Registration Number: CTRI/2023/12/060942
• Lead Sponsor: Government medical college, Bhavnagar

Brief Summary

•After approval from ethics committee, study will be started.

•All the admitted patients for cataract surgery who are fulfilling inclusion criteria And willing to give written informed consent will be taken for the study.

•Pre-operative corneal endothelial cell density, shape and size will be measured by specular microscope (TOPCON SP-1P).

•Patient will be taken for cataract surgery, SICS or Phacoemulsification.

•Post-operative corneal endothelial cell density, shape and size will be measured by specular microscope.(TOPCON SP-1P)

•All the data will be collected and analysed.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-12-23
• Study Start: 2024-03-01

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients >18 years of age undergoing cataract surgery.

Exclusion Criteria

• Cataract patients having-: Glaucoma Any corneal pathology History of chronic ocular inflammation Traumatic cataract Ocular surgeries or ocular trauma in the past.
• Patients with any systemic disease like diabetes.
• Inadvertent surgery.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess corneal endothelial cells injury by small incision cataract surgery versus phacoemulsification in terms of	To assess corneal endothelial cells injury by small incision cataract surgery versus phacoemulsification in terms of | Cell density | Cell shape | Cell size, by specular microscope pre-opertaively and 2 weeks post-operatively
Cell density	To assess corneal endothelial cells injury by small incision cataract surgery versus phacoemulsification in terms of | Cell density | Cell shape | Cell size, by specular microscope pre-opertaively and 2 weeks post-operatively
Cell shape	To assess corneal endothelial cells injury by small incision cataract surgery versus phacoemulsification in terms of | Cell density | Cell shape | Cell size, by specular microscope pre-opertaively and 2 weeks post-operatively
Cell size, by specular microscope.	To assess corneal endothelial cells injury by small incision cataract surgery versus phacoemulsification in terms of | Cell density | Cell shape | Cell size, by specular microscope pre-opertaively and 2 weeks post-operatively

Secondary Outcome Measures

Name	Time	Method
To evaluate post-operative complications	15 months

Trial Locations

Locations (1)

Sir T hospital, Bhavnagar; 🇮🇳 Bhavnagar, GUJARAT, India

Sir T hospital, Bhavnagar

🇮🇳Bhavnagar, GUJARAT, India

Dr swati choudhary

Principal investigator

8000287971

swati93choudhary@gmail.com