跳至主要内容
临床试验/NCT03431038
NCT03431038Unknown不适用

Cross-sectional Study of Prevalence Rate of Abdominal Aortic Aneurysm in OSAHS Patients From BTCH

Beijing Tsinghua Chang Gung Hospital1 个研究点 分布在 1 个国家目标入组 1,800 人开始时间: 2017年9月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
1,800
试验地点
1
主要终点
Diameter of aorta

研究概览

简要总结

This study explore AAA prevalence in OSAHS patients by ultrasound screening and try to analysis risk factors of AAA in OSAHS patients.

详细描述

Abdominal aortic aneurysm (AAA) is an extremely high mortality disease, and ultrasound has been recommended for the screening of AAA, which is highly sensitive and specific. Studies have shown that screening for AAA in the population can significantly reduce deaths from ruptured abdominal aortic aneurysms. However, those study mainly focus on cardiovascular disease patients or general population, no previous study target on obstructive sleep apnea hypopnea syndrome (OSAHS) population. Retrospective studies show that the incidence of apnea syndrome in patients with abdominal aortic aneurysm is higher than that in the control group, which suggests that OSAHS may be one of the causes of abdominal aortic aneurysm. At present, there is no relevant research on the screening of AAA in OSAHS population.

The main objective of this study was to screen the prevalence of AAA in OSAHS population by a cross-sectional study.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
45 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients who accept respiratory sleep monitoring in the department of ENT, BTCH, aged over 45 years, from 2018-01-01 to 2019-12-30

排除标准

  • Any previous diagnosis of AAA history;
  • Received AAA related treatment;
  • Past imaging test result suggested increased diameter of the abdominal aorta.
  • Poor compliance; refused to follow the requirements set in this study follow-up, and refused to sign informed consent.

结局指标

主要结局

Diameter of aorta

时间窗: 0-48 hours

Diameter of aorta measured by ultrasound

次要结局

  • ABI(0-48 hours)
  • Carotid artery stenosis(0-48 hours)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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